慢性淋巴细胞白血病患者出现的抗小管基底膜抗体肾炎：非常罕见的病例报告

IF 0.9 Q3 MEDICINE, GENERAL & INTERNAL Journal of investigative medicine high impact case reports Pub Date : 2024-01-01 DOI:10.1177/23247096241281612

Niloufar Ebrahimi, Behzad Najafian, Yan Chen Wongworawat, Sayna Norouzi, Amir Abdipour

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引用次数: 0

摘要

抗小管基底膜（anti-TBM）抗体肾炎是一种罕见的肾小管间质性肾炎，与肾功能进行性下降有关。它的组织病理学特征是肾小管萎缩和扩张、间质纤维化、淋巴细胞和巨噬细胞为主的细胞浸润以及 IgG 和补体沿肾小管基底膜的线性沉积。我们在此报告了一例 69 岁男性患者的病例，他最近被诊断出患有慢性淋巴细胞白血病（CLL），并被转诊至肾衰竭医院进行评估，最终被诊断为抗 TBM 抗体肾炎，并发展为终末期肾病（ESKD）。本病例报告强调了抗 TBM 抗体肾炎这种罕见肾脏疾病的治疗难题。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Anti-Tubular Basement Membrane Antibody Nephritis Manifesting in a Patient With Chronic Lymphocytic Leukemia: A Very Rare Case Report.

Anti-tubular basement membrane (anti-TBM) antibody nephritis is a rare type of tubulointerstitial nephritis associated with progressive decline in kidney function. It is characterized histopathologically by tubular atrophy and dilation, interstitial fibrosis, lymphocyte and macrophage-predominant cellular infiltration, and linear deposition of IgG and complement along the tubular basement membrane. We herein present a case of a 69-year-old male who was recently diagnosed with chronic lymphocytic leukemia (CLL) and was referred for evaluation of kidney failure, ultimately diagnosed as anti-TBM antibody nephritis progressing into end-stage kidney disease (ESKD). This case report highlights the management challenges of anti-TBM antibody nephritis as a rare kidney disorder.

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来源期刊

Journal of investigative medicine high impact case reports MEDICINE, GENERAL & INTERNAL-

CiteScore

1.90

自引率

0.00%

发文量

165

审稿时长

12 weeks

期刊介绍： The AFMR is committed to enhancing the training and career development of our members and to furthering its mission to facilitate the conduct of research to improve medical care. Case reports represent an important avenue for trainees (interns, residents, and fellows) and early-stage faculty to demonstrate productive, scholarly activity.