[肺栓塞:门诊治疗和随访]。

Deutsche medizinische Wochenschrift (1946) Pub Date : 2024-10-01 Epub Date: 2024-09-23 DOI:10.1055/a-2252-7665
Lukas Hobohm, Karsten Keller
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引用次数: 0

摘要

尽管肺栓塞的发病人数在不断下降,但老年人尤其容易死于肺栓塞。快速评估疑似栓塞的风险、排除合并症和适当的治疗是现行指南的重点。对急性 PE 患者进行早期和后续门诊治疗一般需要满足 3 个标准:早期并发症风险低、无严重合并症、在家中尽可能安全,以及在发生并发症时能迅速到医院接受急诊治疗。对于 VTE 复发风险较高的患者,二次药物预防的长期剂量尚不明确,目前正在进行相关研究。对于 VTE 复发风险中等的患者,可以使用低剂量的二级预防药物来降低出血风险。门诊肺栓塞随访护理变得越来越重要,因为研究多次表明,长期随访可能会造成严重后果。对于持续呼吸困难、表现减弱或有 CTEPH 风险的肺栓塞患者,建议在门诊使用超声心动图对右心室进行评估,必要时结合利钠肽测定或螺线管测定。
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[Pulmonary embolism: outpatient treatment and follow-up].

Despite declining numbers - older people in particular - often die from pulmonary embolism. A rapid assessment of the risk in the event of a suspected embolism, the exclusion of comorbidities and the appropriate therapy are the focus of the current guidelines. Early and subsequent outpatient treatment of a patient with acute PE generally requires 3 criteria: low risk of early complications, the absence of serious comorbidities and the highest possible safety at home and, in the event of a complication, rapid access to acute care in the hospital. For patients with a high risk of VTE recurrence, the long-term dosage of secondary drug prophylaxis is not yet clear - studies are currently underway. In patients at moderate risk of VTE recurrence, low-dose secondary prophylaxis can be used to reduce the risk of bleeding. Outpatient pulmonary embolism follow-up care is becoming increasingly important, because studies have shown several times that serious long-term consequences can occur. In pulmonary embolism patients with persistent dyspnea, reduced performance or risk of CTEPH, an outpatient evaluation of the right ventricle using echocardiography, if necessary, in combination with the determination of natriuretic peptides or spiroergometry, is recommended.

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