用于临床可解释的芝麻骨膜炎分级的多任务学习模型

IF 7 2区 医学 Q1 BIOLOGY Computers in biology and medicine Pub Date : 2024-09-25 DOI:10.1016/j.compbiomed.2024.109179
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引用次数: 0

摘要

趾骨关节炎是一种常见的马病,严重程度不一,会导致马匹受伤的风险增加和性能下降。芝麻骨膜炎的准确分级对于有效治疗至关重要。虽然基于深度学习的芝麻骨炎分级方法前景广阔,但仍未得到充分探索,而且往往缺乏临床可解释性。为了解决这个问题,我们提出了一种新颖的、临床上可解释的多任务学习模型,该模型将临床知识与机器学习相结合。该模型采用双分支解码器,可同时进行芝麻炎分级和血管通道分割。利用特征融合在这些任务之间传递知识,从而能够识别细微的放射学变化。此外,我们的模型还能生成诊断报告,该报告与血管通道掩膜一起解释了模型的分级决定,从而提高了决策过程的透明度。我们在两个数据集上验证了我们的模型,证明其在准确性和概括性方面都优于最先进的模型。这项研究为类似疾病的可解释分级提供了一个基础框架。
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A multi-task learning model for clinically interpretable sesamoiditis grading
Sesamoiditis is a common equine disease with varying severity, leading to increased injury risks and performance degradation in horses. Accurate grading of sesamoiditis is crucial for effective treatment. Although deep learning-based approaches for grading sesamoiditis show promise, they remain underexplored and often lack clinical interpretability. To address this issue, we propose a novel, clinically interpretable multi-task learning model that integrates clinical knowledge with machine learning. The proposed model employs a dual-branch decoder to simultaneously perform sesamoiditis grading and vascular channel segmentation. Feature fusion is utilized to transfer knowledge between these tasks, enabling the identification of subtle radiographic variations. Additionally, our model generates a diagnostic report that, along with the vascular channel mask, serves as an explanation of the model’s grading decisions, thereby increasing the transparency of the decision-making process. We validate our model on two datasets, demonstrating its superior performance compared to state-of-the-art models in terms of accuracy and generalization. This study provides a foundational framework for the interpretable grading of similar diseases.
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来源期刊
Computers in biology and medicine
Computers in biology and medicine 工程技术-工程:生物医学
CiteScore
11.70
自引率
10.40%
发文量
1086
审稿时长
74 days
期刊介绍: Computers in Biology and Medicine is an international forum for sharing groundbreaking advancements in the use of computers in bioscience and medicine. This journal serves as a medium for communicating essential research, instruction, ideas, and information regarding the rapidly evolving field of computer applications in these domains. By encouraging the exchange of knowledge, we aim to facilitate progress and innovation in the utilization of computers in biology and medicine.
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