美国成年人输尿管盆腔梗阻的原发性肾盂成形术,带或不带双 J 型留置输尿管支架。保险理赔数据包括当代移除时间趋势、围手术期并发症、医疗费用和再次介入率。

IF 4.9 2区 医学 Q1 UROLOGY & NEPHROLOGY Minerva Urology and Nephrology Pub Date : 2024-10-01 DOI:10.23736/S2724-6051.24.05834-8
Francesco Del Giudice, Deok Hyun Han, Anas Tresh, Shufeng Li, Satvir Basran, Vincenzo Asero, Carlo Maria Scornajenghi, Dalila Carino, Roberta Corvino, Matteo Ferro, Felice Crocetto, Benjamin Pradere, Andrea Gallioli, Wojciech Krajewski, Łukasz Nowak, Jan Łaszkiewicz, Tomasz Szydełko, Bernardo Rocco, Maria Chiara Sighinolfi, Ettore De Berardinis, Jonathan Kam, Rajesh Nair, Benjamin I Chung
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引用次数: 0

摘要

背景:我们利用一个基于人口的大型数据集,主要目的是比较输尿管盆腔交界处梗阻(UPJO)患者接受支架与非支架肾盂成形术的术后并发症、医疗支出和再次介入率。次要目标是调查影响DJ支架取出时机的因素:方法:使用 Merative™ Marketscan® 数据库对 2007-2021 年间接受初级开放式或微创肾盂成形术治疗的≥18 岁 UPJO 患者进行识别。采用多变量模型研究了双J(DJ)支架置入与肾盂成形术后并发症、住院费用和再次介入率之间的关系,以及围手术期预测因素对DJ支架移除时间的作用。此外,还根据输尿管支架植入时间进行了分组分析:在4872名接受初级肾盂成形术的患者中,4154人(85.3%)植入了DJ支架。术后并发症很少(218 例,4.47%),且与输尿管支架置入无关(几率比 [OR]:0.78,95% 置信区间 [CI]:0.55-1.12)。住院费用的中位数为21,775美元,DJ支架置入可独立增加中位数总额(OR:1.29,95% CI:1.09-1.53)。总体而言,21.18%的患者接受了再次干预,DJ支架置入具有保护作用(OR:0.79,95% CI:0.66-0.96)。较高的夏尔森综合指数、较长的住院时间和开放手术方式是DJ支架取出时间延长的独立预测因素:我们的研究表明,与接受有支架手术的患者相比,接受无支架肾盂成形术的患者确实有更高的二次手术率,但并发症并不高。同时,尽管二次手术率增加,但无支架方法可降低医疗支出。
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Primary pyeloplasty for uretero-pelvic obstruction in the USA adult population with or without double-J indwelling ureteral stents. Insurance claims data on contemporary time to removal trends, perioperative complications, health care costs, and re-intervention rates.

Background: Using a large population-based dataset, we primarily sought to compare postoperative complications, health-care expenditures, and re-intervention rates between patients diagnosed with ureteropelvic junction obstruction (UPJO) undergoing stented vs. non-stented pyeloplasty. The secondary objective was to investigate factors that influence the timing of DJ stent removal.

Methods: Patients ≥18 years old with UPJO treated with primary open or minimally-invasive pyeloplasty were identified using the Merative™ Marketscan® Databases between 2007-2021. Multivariable modeling was implemented to investigate the association between Double-J (DJ) stent placement and post-pyeloplasty complications, hospital costs, and re-intervention rates and the role of the perioperative predictors on time to DJ stent removal. Subgroup analyses stratified by ureteral stenting duration were additionally performed.

Results: Out of 4872 patients who underwent primary pyeloplasty, 4154 (85.3%) had DJ placement. Postoperative complications were rare (N.=218, 4.47%) and not associated with ureteral stenting (odds ratio [OR]: 0.78, 95% confidence interval [CI]: 0.55-1.12). The median cost for in-hospital charges was $21,775, with DJ stent placement independently increasing the median aggregate amount (OR: 1.29, 95% CI: 1.09-1.53). Overall, re-interventions were performed in 21.18% of patients, with DJ stenting found to be protective (OR: 0.79, 95% CI: 0.66-0.96). Higher Charlson Comorbidity Index, longer hospital stay, and open surgical approach were independent predictors for prolonged DJ stenting time to removal.

Conclusions: Our study suggests that patients undergoing stent-less pyeloplasty did have a higher rate of secondary procedures, but not higher complications when compared to those undergoing stented procedures. Concurrently, the non-stented approach is associated with decreased health-care expenditures, despite the increased rates of secondary procedures.

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来源期刊
Minerva Urology and Nephrology
Minerva Urology and Nephrology UROLOGY & NEPHROLOGY-
CiteScore
8.50
自引率
32.70%
发文量
237
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