Cristián Mansilla, Qi Wang, Thomas Piggott, Peter Bragge, Kerry Waddell, Gordon Guyatt, Arthur Sweetman, John N Lavis
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This critical interpretive synthesis answers the questions: What constitutes an LES to support decision-making?; when should one be produced, updated, and discontinued?; and how should one be disseminated?</p><p><strong>Methods: </strong>Searches included the Cochrane Library, EMBASE (Ovid), Health Systems Evidence, MEDLINE (Ovid), PubMed, and Web of Science up to 23 April 2024 and included articles that provide any insights on addressing the compass questions on LESs. Articles were selected and appraised, and their insights extracted. An interpretive and iterative coding process was used to identify relevant thematic categories and create a conceptual framework.</p><p><strong>Results: </strong>Among the 16,630 non-duplicate records identified, 208 publications proved eligible. Most were non-empirical articles, followed by actual LESs. Approximately one in three articles were published in response to the COVID-19 pandemic. 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引用次数: 0
摘要
背景：COVID-19 大流行对全球研究成果产生了前所未有的影响，同时也增加了研究浪费。活证据综述（LES）旨在定期更新针对特定问题的一整套证据。在 COVID-19 大流行期间，活证据综述的制作和传播成为证据基础设施的基石。这篇重要的解释性综述回答了以下问题：什么是支持决策的 LES？何时应编制、更新和终止 LES？搜索范围包括 Cochrane Library、EMBASE (Ovid)、Health Systems Evidence、MEDLINE (Ovid)、PubMed 和 Web of Science，搜索时间截止到 2024 年 4 月 23 日，其中包括对解决 LES 指南问题有任何见解的文章。对文章进行了筛选和评估，并提取了其观点。采用解释性和迭代式编码过程确定相关主题类别并创建概念框架：在已确定的 16,630 条非重复记录中，有 208 篇出版物符合条件。大部分是非实证性文章，其次是实际的 LES。大约每三篇文章中就有一篇是针对 COVID-19 大流行发表的。该概念框架涉及六个专题类别：（1）什么是 LES；（2）哪些方法有利于 LES 的编制；（3）何时编制 LES；（4）何时更新 LES；（5）如何提供 LES 的研究结果；以及（6）何时停止 LES 的更新：LES 可在减少研究浪费、确保与咨询和决策过程保持一致方面发挥关键作用。这篇重要的解释性综述就如何更好地组织全球证据架构以支持其生产提供了相关见解：试验注册：PROSPERO 注册：CRD42021241875。
A living critical interpretive synthesis to yield a framework on the production and dissemination of living evidence syntheses for decision-making.
Background: The COVID-19 pandemic has had an unprecedented impact in the global research production and has also increased research waste. Living evidence syntheses (LESs) seek to regularly update a body of evidence addressing a specific question. During the COVID-19 pandemic, the production and dissemination of LESs emerged as a cornerstone of the evidence infrastructure. This critical interpretive synthesis answers the questions: What constitutes an LES to support decision-making?; when should one be produced, updated, and discontinued?; and how should one be disseminated?
Methods: Searches included the Cochrane Library, EMBASE (Ovid), Health Systems Evidence, MEDLINE (Ovid), PubMed, and Web of Science up to 23 April 2024 and included articles that provide any insights on addressing the compass questions on LESs. Articles were selected and appraised, and their insights extracted. An interpretive and iterative coding process was used to identify relevant thematic categories and create a conceptual framework.
Results: Among the 16,630 non-duplicate records identified, 208 publications proved eligible. Most were non-empirical articles, followed by actual LESs. Approximately one in three articles were published in response to the COVID-19 pandemic. The conceptual framework addresses six thematic categories: (1) what is an LES; (2) what methodological approaches facilitate LESs production; (3) when to produce an LES; (4) when to update an LES; (5) how to make available the findings of an LES; and (6) when to discontinue LES updates.
Conclusion: LESs can play a critical role in reducing research waste and ensuring alignment with advisory and decision-making processes. This critical interpretive synthesis provides relevant insights on how to better organize the global evidence architecture to support their production.
期刊介绍：
Implementation Science is a leading journal committed to disseminating evidence on methods for integrating research findings into routine healthcare practice and policy. It offers a multidisciplinary platform for studying implementation strategies, encompassing their development, outcomes, economics, processes, and associated factors. The journal prioritizes rigorous studies and innovative, theory-based approaches, covering implementation science across various healthcare services and settings.
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