Victoria Wang MD , Kevin M. Elias MD , Ross S. Berkowitz MD , Neil S. Horowitz MD
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引用次数: 0
摘要
胎盘部位滋养细胞疾病（PSTT）和上皮样滋养细胞肿瘤（ETT）是最罕见的妊娠滋养细胞肿瘤（GTN），具有独特的临床特征和治疗注意事项。与其他 GTN 不同的是，人绒毛膜促性腺激素（hCG）即使升高也是微乎其微的。此外，与其他 GTN 不同，PSTT/ETT 不采用 WHO 风险评分。PSTT/ETT 的治疗方法主要是手术，包括子宫切除术和可能的淋巴结切除术。有病例报告称，对子宫局限性疾病进行了保胎手术。对于具有高风险特征的患者，即晚期患者和确诊时距离前次妊娠≥48个月的患者，可加用多药化疗和pembrolizumab。早期、低风险疾病的生存率仍然很高，但高风险疾病的预后较差，需要采用新的治疗方法。
期刊介绍：
Hematology/Oncology Clinics updates you on the latest trends in patient management, keeps you up to date on the newest advances, and provides a sound basis for choosing treatment options. Under the direction of an experienced guest editor, each issue focuses on a single topic in hematology and oncology, including hemostasis and thrombosis, molecular and cellular basis of hematology, coagulation disorders, and cancers—bone, gastrointestinal, head and neck, lymphomas, neuroendocrine, breast, renal cell, melanoma, and more.
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