使用微调 CNN 和残余 UNet 架构同时进行脑肿瘤分类和分割的统一管道。

IF 3.2 3区 生物学 Q1 BIOLOGY Life-Basel Pub Date : 2024-09-10 DOI:10.3390/life14091143
Faisal Alshomrani
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引用次数: 0

摘要

在本文中,我介绍了一种集成微调卷积神经网络(FT-CNN)和残差-UNet(RUNet)架构的综合管道,用于自动分析核磁共振成像脑部扫描图像。该系统解决了脑肿瘤分类和分割的双重难题,而这两项任务在医学图像分析中对于精确诊断和治疗规划至关重要。首先,管道对 FigShare 脑部 MRI 图像数据集(包括 3064 幅图像)进行预处理,对其进行归一化和大小调整,以实现与模型的统一性和兼容性。然后,FT-CNN 模型将预处理后的图像分类为不同的肿瘤类型:胶质瘤、脑膜瘤和垂体瘤。分类后,RUNet 模型执行像素级分割,在核磁共振成像扫描中划分肿瘤区域。FT-CNN 利用 VGG19 架构,在大型数据集上进行预训练,并针对特定肿瘤分类任务进行微调。从核磁共振成像图像中提取的特征用于训练 FT-CNN,在区分肿瘤类型方面表现出强劲的性能。随后,RUNet 模型受到 U-Net 设计的启发,并利用残余块进行了增强,通过将编码路径的高分辨率空间信息与瓶颈处的丰富上下文特征相结合,有效地分割了肿瘤。我的实验结果表明,集成管道在分类(96%)和分割任务(98%)中都达到了很高的准确率,展示了其在脑肿瘤诊断中的临床应用潜力。在分类任务中,涉及的指标有损失、准确率、混淆矩阵和分类报告;在分割任务中,使用的指标有损失、准确率、Dice系数、交集大于联合和Jaccard距离。为了进一步验证集成管道的通用性和鲁棒性,我在另外两个数据集上对模型进行了评估。第一个数据集包含用于分类任务的 7023 幅图像,扩展为四类数据集。第二个数据集包含约 3929 张图像,用于分类和分割任务,包括二元分类场景。该模型表现稳健,在四类任务中达到 95% 的准确率,在二元分类和分割任务中达到较高的准确率(96%),Dice 系数为 95%。
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A Unified Pipeline for Simultaneous Brain Tumor Classification and Segmentation Using Fine-Tuned CNN and Residual UNet Architecture.

In this paper, I present a comprehensive pipeline integrating a Fine-Tuned Convolutional Neural Network (FT-CNN) and a Residual-UNet (RUNet) architecture for the automated analysis of MRI brain scans. The proposed system addresses the dual challenges of brain tumor classification and segmentation, which are crucial tasks in medical image analysis for precise diagnosis and treatment planning. Initially, the pipeline preprocesses the FigShare brain MRI image dataset, comprising 3064 images, by normalizing and resizing them to achieve uniformity and compatibility with the model. The FT-CNN model then classifies the preprocessed images into distinct tumor types: glioma, meningioma, and pituitary tumor. Following classification, the RUNet model performs pixel-level segmentation to delineate tumor regions within the MRI scans. The FT-CNN leverages the VGG19 architecture, pre-trained on large datasets and fine-tuned for specific tumor classification tasks. Features extracted from MRI images are used to train the FT-CNN, demonstrating robust performance in discriminating between tumor types. Subsequently, the RUNet model, inspired by the U-Net design and enhanced with residual blocks, effectively segments tumors by combining high-resolution spatial information from the encoding path with context-rich features from the bottleneck. My experimental results indicate that the integrated pipeline achieves high accuracy in both classification (96%) and segmentation tasks (98%), showcasing its potential for clinical applications in brain tumor diagnosis. For the classification task, the metrics involved are loss, accuracy, confusion matrix, and classification report, while for the segmentation task, the metrics used are loss, accuracy, Dice coefficient, intersection over union, and Jaccard distance. To further validate the generalizability and robustness of the integrated pipeline, I evaluated the model on two additional datasets. The first dataset consists of 7023 images for classification tasks, expanding to a four-class dataset. The second dataset contains approximately 3929 images for both classification and segmentation tasks, including a binary classification scenario. The model demonstrated robust performance, achieving 95% accuracy on the four-class task and high accuracy (96%) in the binary classification and segmentation tasks, with a Dice coefficient of 95%.

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来源期刊
Life-Basel
Life-Basel Biochemistry, Genetics and Molecular Biology-General Biochemistry,Genetics and Molecular Biology
CiteScore
4.30
自引率
6.20%
发文量
1798
审稿时长
11 weeks
期刊介绍: Life (ISSN 2075-1729) is an international, peer-reviewed open access journal of scientific studies related to fundamental themes in Life Sciences, especially those concerned with the origins of life and evolution of biosystems. Our aim is to encourage scientists to publish their experimental and theoretical results in as much detail as possible. There is no restriction on the length of the papers.
期刊最新文献
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