1 型糖尿病患者饮食习惯与血糖控制之间的相互作用:一项全面的前瞻性 FGM 研究。

IF 3.2 3区 生物学 Q1 BIOLOGY Life-Basel Pub Date : 2024-09-12 DOI:10.3390/life14091153
Maja Gradinjan Centner, Daniela Čačić Kenjerić, Ema Schönberger, Hrvoje Centner, Daria Sladić Rimac, Kristina Steiner, Romana Marušić, Miro Bakula, Daniela Fabris Vitković, Ivica Mihaljević, Ines Bilić Ćurčić, Silvija Canecki Varžić
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引用次数: 0

摘要

1 型糖尿病已成为成年人群中的流行病,他们越来越多地接触到传感技术。本研究深入探讨了饮食、营养状况和连续血糖监测系统(CGM)的使用对确诊为 1 型糖尿病的成年人血糖调节的影响。该研究采用前瞻性设计,从 151 名 18-60 岁的参与者中收集了多个周期的数据。参与者使用了 FreeStyle Libre(FSL)闪存葡萄糖监测(FGM)系统,并通过问卷和日记提供了饮食细节。研究结果揭示了饮食模式与血糖控制之间的相关性,蛋白质摄入量越高,糖化血红蛋白 A1C 值就越高(p = 0.019),而脂肪和蛋白质摄入量越高,高血糖发生率就越高。相反,在饮食变量和低血糖发生率之间没有观察到明显的关系。有趣的是,血糖读数较高的受试者摄入的碳水化合物较少(p = 0.004),而摄入的蛋白质较多(p = 0.000)。此外,体育锻炼和婚姻状况与血糖稳定性相关,而教育程度越高,血糖控制越好(p = 0.021)。这项研究证实了有组织的血糖调节教育的重要性,以及饮食模式在血糖管理中的重要性。此外,还证实了 FGM 系统在改变饮食习惯方面的教育作用,而这正是改善连续血糖监测系统用户血糖调节的关键因素之一。
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The Interplay between Dietary Habits and Glycemic Control in Type 1 Diabetes: A Comprehensive Prospective FGM Study.

Type 1 diabetes has become prevalent among the adult population, who have increasingly gained access to sensing technology. This study delved into the impact of diet, nutritional status, and the use of a continuous glucose monitoring system (CGM) on glycemic regulation among adults diagnosed with T1D. Employing a prospective design, data were gathered from 151 participants aged 18-60 across multiple cycles. Participants utilized the FreeStyle Libre (FSL) Flash Glucose Monitoring (FGM) System and provided dietary details via questionnaires and diaries. The findings unveiled correlations between dietary patterns and glycemic control, with higher protein intake associated with improved glycated hemoglobin A1C values (p = 0.019), yet elevated fat and protein consumption was linked to heightened rates of hyperglycemia. Conversely, no significant relationship was observed between dietary variables and hypoglycemia occurrence. Interestingly, subjects with more readings of glucose levels consumed fewer carbohydrates (p = 0.004) and more proteins (p = 0.000). Furthermore, physical activity and marital status correlated with glycemic stability, while higher education was associated with enhanced glycemic control (p = 0.021). This study confirmed the importance of structured education on glycemic regulation and the importance of dietary patterns in glucose management. Also, the educational role of the FGM system in changing dietary habits was confirmed, which is one of the key factors for improving glycemic regulation in continuous glucose monitoring system users.

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来源期刊
Life-Basel
Life-Basel Biochemistry, Genetics and Molecular Biology-General Biochemistry,Genetics and Molecular Biology
CiteScore
4.30
自引率
6.20%
发文量
1798
审稿时长
11 weeks
期刊介绍: Life (ISSN 2075-1729) is an international, peer-reviewed open access journal of scientific studies related to fundamental themes in Life Sciences, especially those concerned with the origins of life and evolution of biosystems. Our aim is to encourage scientists to publish their experimental and theoretical results in as much detail as possible. There is no restriction on the length of the papers.
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