单纯后路清创术、椎间融合术和内固定术治疗上胸椎结核的临床效果。

Tao Zhang, Songkai Li, Lihua Ma, Hua Liu, Chengwei Yang, Lian Zhang
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摘要

本研究旨在评估单纯后路清创、椎间融合和内固定术治疗上胸椎结核的有效性和可行性。本研究回顾性分析了 8 名确诊为上胸椎结核患者的临床和影像学数据。所有患者均接受了后路清创术、椎间融合术和内固定术。我们对视觉模拟量表(VAS)、Oswestry残疾指数(ODI)评分、红细胞沉降率(ESR)、C反应蛋白(CRP)、ASIA评分和椎体后凸Cobb角进行了术前和术后评估。背痛和下肢无力是最常见的症状。手术平均持续时间、失血量和术后引流量分别为 262.5 ± 43.3 分钟、625.0 ± 333.8 毫升和 285.0 ± 118.1 毫升。对患者进行了 36 至 48 个月的随访。术后三个月,VAS 和 ODI 评分明显改善,并在最后一次随访前进一步改善。术前和术后的差异有统计学意义(P < .05)。在最后的随访中,5 位瘫痪患者的下肢功能均已完全恢复正常。术后 3 个月内,血沉和 CRP 恢复正常,分别为 18.1 ± 7.3 mm/h 和 9.95 ± 5.41 mg/L。术前和术后存在统计学差异(P < .05)。平均畸形矫正率为 (71.5 ± 7.3)%,平均矫正角度损失为 (3.5 ± 1.4)°。所有患者均在术后 15 个月内(平均 8.3 ± 3.2 个月)实现了椎骨融合。单纯后路治疗上胸椎结核似乎是一种有效、安全、可靠的治疗方法,具有良好的临床和影像学效果。IV级,治疗性研究。
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Clinical effect of posterior-only approach debridement, intervertebral fusion, and internal fixation for upper thoracic tuberculosis.

This study aimed to evaluate the effectiveness and feasibility of the posterior-only approach for debridement, interbody fusion, and internal fixation in treating upper thoracic tuberculosis. This study retrospectively analysed the clinical and radiographic data of 8 patients diagnosed with upper thoracic tuberculosis. All patients underwent posterior approach debridement, interbody fusion, and internal fixation. We conducted pre- and postoperative assessments of the visual analog scale (VAS), Oswestry disability index (ODI) scores, erythrocyte sedimentation rate (ESR), C-reactive protein (CRP), ASIA score, and kyphotic Cobb angle. Back pain and lower limb weakness were the most common presenting symptoms. The mean duration of surgery, amount of blood loss, and volume of postoperative drainage were 262.5 ± 43.3 min, 625.0 ± 333.8 mL, and 285.0 ± 118.1 mL, respectively. Patients were followed up for 36 to 48 months. Three months after surgery, there was a significant improvement in VAS and ODI scores, which further improved until the final follow-up. A statistically significant difference was observed between the preoperative and postoperative periods (P < .05). At the final follow-up, lower extremity function had fully returned to normal in all 5 paralyzed patients. The ESR and CRP returned to normal, 18.1 ± 7.3 mm/h and 9.95 ± 5.41 mg/L, respectively, within 3 months postoperatively. There were statistical differences between the preoperative and postoperative periods (P < .05). The average kyphotic correction rate was (71.5 ± 7.3)%, and the average loss of correction angle was (3.5 ± 1.4)°. Intervertebral bone fusion was achieved by all patients within 15 months (mean 8.3 ± 3.2 months) postoperatively. The posterior-only approach seems an effective, safe, and reliable treatment method for upper thoracic tuberculosis, with favourable clinical and radiological outcomes. Level IV, Therapeutic study.

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