接受血液透析和移植手术的终末期肾病患者的生活质量和心理压力。

Emad A Shdaifat, Firas T Abu-Sneineh, Abdallah M Ibrahim
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引用次数: 0

摘要

背景:终末期肾病(ESRD)对患者的生活质量(QoL)产生了各种深远的影响,其中抑郁、焦虑和压力的程度经常会增加。血液透析(HD)和移植(TX)等肾脏替代疗法旨在提高患者的生活质量,但这些疗法能否减轻患者的心理压力仍不确定。本研究认为,在 ESRD 患者中,负面情绪状态与 QoL 之间存在显著相关性,在 HD 和 TX 患者中观察到的效果各不相同。目的:研究 QoL 与负面情绪状态(抑郁、焦虑和压力)之间的关系,以及各种 ESRD 终末期肾替代疗法患者的预测 QoL:这项横断面研究包括沙特阿拉伯东部地区的 HD 或 TX 患者。数据收集采用了 36 项简表调查和抑郁焦虑压力量表(DASS),并进行了相关和回归分析:结果:HD 和 TX 移植组的 QoL 与 DASS 评分之间存在统计学意义上的显著反比关系。焦虑程度高、受教育程度低的 HD 患者在身体成分总结(PCS)中得分较低。此外,精神部分摘要(MCS)的结果与抑郁程度降低有关。与年龄较大的移植患者相比,TX 患者的 PCS 分数较低,抑郁、压力和消极的工作条件与 MCS 分数高度相关:本研究的结果表明,接受 HD 和 TX 患者的幸福感与精神压力之间存在显著联系。HD 患者的 PCS 受焦虑水平升高和教育程度降低的影响,而移植患者的 MCS 则受年龄增长和压力水平升高的影响。这些见解将有助于更全面地了解患者支持。
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Quality of life and psychological distress in end-stage renal disease patients undergoing hemodialysis and transplantation.

Background: Among diverse profound impacts on patients' quality of life (QoL), end-stage renal disease (ESRD) frequently results in increased levels of depression, anxiety, and stress. Renal replacement therapies such as hemodialysis (HD) and transplantation (TX) are intended to enhance QoL, although their ability to alleviate psychological distress remains uncertain. This research posits the existence of a significant correlation between negative emotional states and QoL among ESRD patients, with varying effects observed in HD and TX patients.

Aim: To examine the relationship between QoL and negative emotional states (depression, anxiety, and stress) and predicted QoL in various end-stage renal replacement therapy patients with ESRD.

Methods: This cross-sectional study included HD or TX patients in the Eastern Region of Saudi Arabia. The 36-item Short Form Survey and Depression Anxiety Stress Scale (DASS) was used for data collection, and correlation and regression analyses were performed.

Results: The HD and TX transplantation groups showed statistically significant inverse relationships between QoL and DASS scores. HD patients with high anxiety levels and less education scored low on the physical component summary (PCS). In addition, the results of the mental component summary (MCS) were associated with reduced depression. Compared with older transplant patients, TX patients' PCS scores were lower, and depression, stress, and negative working conditions were highly correlated with MCS scores.

Conclusion: The findings of this study revealed notable connections between well-being and mental turmoil experienced by individuals undergoing HD and TX. The PCS of HD patients is affected by heightened levels of anxiety and lower educational attainment, while the MCS of transplant patients is influenced by advancing age and elevated stress levels. These insights will contribute to a more comprehensive understanding of patient support.

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