巴基斯坦人对基因检测的看法:一项关于知识、态度、认识和担忧的调查。

IF 1.5 Q4 GENETICS & HEREDITY Journal of Community Genetics Pub Date : 2024-10-01 DOI:10.1007/s12687-024-00719-6
Mohammad Uzair, Rida Fatima, Shafia Rafiq, Maimoona Jabeen, Hammad Qaiser, Muhammad Arshad, Shahid Bashir
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引用次数: 0

摘要

近亲结婚率的升高与遗传性疾病发病率的增加有关,给家庭、公共卫生和医疗保健系统带来了沉重负担。基因检测有助于更早地发现疾病和个性化治疗方法。因此,本研究旨在评估巴基斯坦人对基因检测的了解、认识、态度和担忧。参与者(n = 494)被问及影响接受基因检测态度的因素。此外,本研究还调查了巴基斯坦人对基因检测的担忧和保留意见。受访者表示,近亲结婚会导致遗传性疾病的风险增加,并认为了解遗传性疾病的知识可以提高生活质量。近 80% 的受访者知道 "基因检测 "这一术语,其中大多数人知道基因检测。87.7% 的受访者同意婚前进行基因筛查,39.9% 的受访者愿意接受基因检测。更多的知识与接受基因检测的可能性明显相关,这表明如果将基因检测纳入标准程序,可能会被接受。有遗传疾病家族史的受访者接受基因检测的积极性更高。对基因检测的了解程度也会影响人们的顾虑。文化或宗教信仰也会影响接受基因检测的决定。调查显示,巴基斯坦人对基因检测的看法和了解程度各不相同。虽然人们普遍对基因检测抱有积极的兴趣,但对隐私、准确性和文化因素的担忧也应得到解决。教育和宣传活动有助于提高人们的理解和接受程度。
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Genetic testing perspectives in Pakistani population: a survey on knowledge, attitudes, awareness, and concerns.

A higher rate of consanguineous marriages is associated with the increasing prevalence of genetic disorders, imposing a significant burden on families, public health, and healthcare systems. Genetic testing facilitates the earlier detection of disease and personalized treatment approaches. Therefore, this study aims to assess knowledge, awareness, attitudes, and concerns regarding genetic testing in the Pakistani population. Participants (n = 494) were asked about factors that influence attitudes toward undergoing genetic testing. Furthermore, the study also investigates the concerns and reservations held by the Pakistani population regarding genetic testing. Participants indicated that consanguineous marriages lead to an increased risk of hereditary disorders and agreed that knowledge of genetic diseases can improve the quality of life. Almost 80% of the respondents know the term, and the majority of them know about genetic testing. 87.7% of respondents agreed to genetic screening before marriage, and 39.9% were willing to undergo genetic testing. More knowledge was significantly associated with a higher likelihood of accepting genetic testing, indicating potential acceptance if integrated into standard procedures. Those with a family history of genetic disorders were more positive in accepting genetic testing. The level of understanding regarding genetic testing also influences the concerns. Cultural or religious beliefs may also affect the decision to accept genetic testing. The survey reveals diverse opinions and knowledge levels regarding genetic testing in Pakistan. While there was generally positive interest, concerns about privacy, accuracy, and cultural factors should be addressed. Education and awareness campaigns could help improve understanding and acceptance.

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来源期刊
Journal of Community Genetics
Journal of Community Genetics GENETICS & HEREDITY-
CiteScore
3.30
自引率
5.30%
发文量
54
期刊介绍: The Journal of Community Genetics is an international forum for research in the ever-expanding field of community genetics, the art and science of applying medical genetics to human communities for the benefit of their individuals. Community genetics comprises all activities which identify persons at increased genetic risk and has an interest in assessing this risk, in order to enable those at risk to make informed decisions. Community genetics services thus encompass such activities as genetic screening, registration of genetic conditions in the population, routine preconceptional and prenatal genetic consultations, public education on genetic issues, and public debate on related ethical issues. The Journal of Community Genetics has a multidisciplinary scope. It covers medical genetics, epidemiology, genetics in primary care, public health aspects of genetics, and ethical, legal, social and economic issues. Its intention is to serve as a forum for community genetics worldwide, with a focus on low- and middle-income countries. The journal features original research papers, reviews, short communications, program reports, news, and correspondence. Program reports describe illustrative projects in the field of community genetics, e.g., design and progress of an educational program or the protocol and achievement of a gene bank. Case reports describing individual patients are not accepted.
期刊最新文献
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