中国广东省通过梅花(药食同源)消费进行重金属和概率风险评估。

IF 2.2 4区 医学 Q3 TOXICOLOGY Toxicology Research Pub Date : 2024-09-24 eCollection Date: 2024-10-01 DOI:10.1093/toxres/tfae142
Rui Huang, Shaowei Chen, Ping Wang, Pan Zhu, Xiumin Xu, Zihui Chen, Jiewen Peng
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引用次数: 0

摘要

毛蕊花在东南亚被广泛用作花草茶的主要成分,也是一种传统中药。然而,由于周围环境污染、种植和加工污染,普通樱草中的砷、镉、汞和铅等重金属污染可能会引起人们的关注。因此,本研究旨在评估因累积接触四种重金属而导致的非致癌风险和致癌风险。本研究测定了 90 批 P. vulgaris 的重金属污染水平。通过对广东省 6 235 名成年参与者进行问卷调查,获得了他们的消费水平。该研究采用蒙特卡洛模拟法对健康风险进行了概率估算,结果发现,菠萝的累积非致癌风险(HI 值)和致癌风险(TCR 值)的估算均值和第 95 百分位数均在可接受的风险范围内。评估结果表明,砷是通过食用 P. vulgaris 导致非致癌和致癌风险的主要因素。这些发现以及继续监测茨菰中的重金属对消费者和政策制定者都具有特别重要的意义。
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Heavy metals and probabilistic risk assessment via Prunella vulgaris (food and medicine homology) consumption in Guangdong Province, China.

Prunella vulgaris is widely used as the main ingredient of herb tea in Southeast Asia, as well as a traditional Chinese medicine. However, the heavy metal contaminations such as arsenic, cadmium, mercury and lead in P. vulgaris may be a cause for concern due to the environment pollution around, plantation and processing contamination. Thus, this study intented to assess both non-carcinogenic risks and carcinogenic risks attributed to cumulative exposure to the four heavy metals in P. vulgaris. The contaminations levels of heavy metals were determined in 90 batches of P. vulgaris. And the consumption level was obtained through a questionnaire survey among a total of 6,235 adult participants in Guangdong province. This study estimated the probabilistic health risks using Monte Carlo simulation, and found that the estimated mean and the 95th percentile values for cumulative noncarcinogenic risk (HI value) and carcinogenic risk (TCR value) of P. vulgaris were all within the acceptable risk. And the assessment results indicated that arsenic was the primary contributors to both noncarcinogenic and carcinogenic risks through P. vulgaris consumption. These findings and continuing the surveillance of heavy metals in P. vulgaris will be particularly relevant to both consumers and policy makers.

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来源期刊
Toxicology Research
Toxicology Research TOXICOLOGY-
CiteScore
3.60
自引率
0.00%
发文量
82
期刊介绍: A multi-disciplinary journal covering the best research in both fundamental and applied aspects of toxicology
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