中国广东省通过梅花(药食同源)消费进行重金属和概率风险评估。

IF 2.2 4区 医学 Q3 TOXICOLOGY Toxicology Research Pub Date : 2024-09-24 eCollection Date: 2024-10-01 DOI:10.1093/toxres/tfae142
Rui Huang, Shaowei Chen, Ping Wang, Pan Zhu, Xiumin Xu, Zihui Chen, Jiewen Peng
{"title":"中国广东省通过梅花(药食同源)消费进行重金属和概率风险评估。","authors":"Rui Huang, Shaowei Chen, Ping Wang, Pan Zhu, Xiumin Xu, Zihui Chen, Jiewen Peng","doi":"10.1093/toxres/tfae142","DOIUrl":null,"url":null,"abstract":"<p><p><i>Prunella vulgaris</i> is widely used as the main ingredient of herb tea in Southeast Asia, as well as a traditional Chinese medicine. However, the heavy metal contaminations such as arsenic, cadmium, mercury and lead in <i>P. vulgaris</i> may be a cause for concern due to the environment pollution around, plantation and processing contamination. Thus, this study intented to assess both non-carcinogenic risks and carcinogenic risks attributed to cumulative exposure to the four heavy metals in <i>P. vulgaris.</i> The contaminations levels of heavy metals were determined in 90 batches of <i>P. vulgaris.</i> And the consumption level was obtained through a questionnaire survey among a total of 6,235 adult participants in Guangdong province. This study estimated the probabilistic health risks using Monte Carlo simulation, and found that the estimated mean and the 95th percentile values for cumulative noncarcinogenic risk (HI value) and carcinogenic risk (TCR value) of <i>P. vulgaris</i> were all within the acceptable risk. And the assessment results indicated that arsenic was the primary contributors to both noncarcinogenic and carcinogenic risks through <i>P. vulgaris</i> consumption. These findings and continuing the surveillance of heavy metals in <i>P. vulgaris</i> will be particularly relevant to both consumers and policy makers.</p>","PeriodicalId":105,"journal":{"name":"Toxicology Research","volume":null,"pages":null},"PeriodicalIF":2.2000,"publicationDate":"2024-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11420550/pdf/","citationCount":"0","resultStr":"{\"title\":\"Heavy metals and probabilistic risk assessment via <i>Prunella vulgaris</i> (food and medicine homology) consumption in Guangdong Province, China.\",\"authors\":\"Rui Huang, Shaowei Chen, Ping Wang, Pan Zhu, Xiumin Xu, Zihui Chen, Jiewen Peng\",\"doi\":\"10.1093/toxres/tfae142\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p><i>Prunella vulgaris</i> is widely used as the main ingredient of herb tea in Southeast Asia, as well as a traditional Chinese medicine. However, the heavy metal contaminations such as arsenic, cadmium, mercury and lead in <i>P. vulgaris</i> may be a cause for concern due to the environment pollution around, plantation and processing contamination. Thus, this study intented to assess both non-carcinogenic risks and carcinogenic risks attributed to cumulative exposure to the four heavy metals in <i>P. vulgaris.</i> The contaminations levels of heavy metals were determined in 90 batches of <i>P. vulgaris.</i> And the consumption level was obtained through a questionnaire survey among a total of 6,235 adult participants in Guangdong province. This study estimated the probabilistic health risks using Monte Carlo simulation, and found that the estimated mean and the 95th percentile values for cumulative noncarcinogenic risk (HI value) and carcinogenic risk (TCR value) of <i>P. vulgaris</i> were all within the acceptable risk. And the assessment results indicated that arsenic was the primary contributors to both noncarcinogenic and carcinogenic risks through <i>P. vulgaris</i> consumption. These findings and continuing the surveillance of heavy metals in <i>P. vulgaris</i> will be particularly relevant to both consumers and policy makers.</p>\",\"PeriodicalId\":105,\"journal\":{\"name\":\"Toxicology Research\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":2.2000,\"publicationDate\":\"2024-09-24\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11420550/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Toxicology Research\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1093/toxres/tfae142\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2024/10/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"Q3\",\"JCRName\":\"TOXICOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Toxicology Research","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1093/toxres/tfae142","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/10/1 0:00:00","PubModel":"eCollection","JCR":"Q3","JCRName":"TOXICOLOGY","Score":null,"Total":0}
引用次数: 0

摘要

毛蕊花在东南亚被广泛用作花草茶的主要成分,也是一种传统中药。然而,由于周围环境污染、种植和加工污染,普通樱草中的砷、镉、汞和铅等重金属污染可能会引起人们的关注。因此,本研究旨在评估因累积接触四种重金属而导致的非致癌风险和致癌风险。本研究测定了 90 批 P. vulgaris 的重金属污染水平。通过对广东省 6 235 名成年参与者进行问卷调查,获得了他们的消费水平。该研究采用蒙特卡洛模拟法对健康风险进行了概率估算,结果发现,菠萝的累积非致癌风险(HI 值)和致癌风险(TCR 值)的估算均值和第 95 百分位数均在可接受的风险范围内。评估结果表明,砷是通过食用 P. vulgaris 导致非致癌和致癌风险的主要因素。这些发现以及继续监测茨菰中的重金属对消费者和政策制定者都具有特别重要的意义。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
Heavy metals and probabilistic risk assessment via Prunella vulgaris (food and medicine homology) consumption in Guangdong Province, China.

Prunella vulgaris is widely used as the main ingredient of herb tea in Southeast Asia, as well as a traditional Chinese medicine. However, the heavy metal contaminations such as arsenic, cadmium, mercury and lead in P. vulgaris may be a cause for concern due to the environment pollution around, plantation and processing contamination. Thus, this study intented to assess both non-carcinogenic risks and carcinogenic risks attributed to cumulative exposure to the four heavy metals in P. vulgaris. The contaminations levels of heavy metals were determined in 90 batches of P. vulgaris. And the consumption level was obtained through a questionnaire survey among a total of 6,235 adult participants in Guangdong province. This study estimated the probabilistic health risks using Monte Carlo simulation, and found that the estimated mean and the 95th percentile values for cumulative noncarcinogenic risk (HI value) and carcinogenic risk (TCR value) of P. vulgaris were all within the acceptable risk. And the assessment results indicated that arsenic was the primary contributors to both noncarcinogenic and carcinogenic risks through P. vulgaris consumption. These findings and continuing the surveillance of heavy metals in P. vulgaris will be particularly relevant to both consumers and policy makers.

求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
Toxicology Research
Toxicology Research TOXICOLOGY-
CiteScore
3.60
自引率
0.00%
发文量
82
期刊介绍: A multi-disciplinary journal covering the best research in both fundamental and applied aspects of toxicology
期刊最新文献
Design and computational analysis of a novel Azurin-BR2 chimeric protein against breast cancer. Synergistic effect of curcumin and Piperine loaded Niosomal nanoparticles on acute pulmonary toxicity induced by Paraquat in mice. Upregulation of ACSL, ND75, Vha26 and sesB genes by antiepileptic drugs resulted in genotoxicity in drosophila. Potential protective role of chlorogenic acid against cyclophosphamide-induced reproductive damage in male mice. The cliff-edge of toxicological concern: highlighting the potential issues of an over-reliance on "less-than-lifetime" thresholds.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1