将胎盘作为自体移植的来源,用于脊髓空洞症的产后矫正。

IF 1.3 4区 医学 Q4 CLINICAL NEUROLOGY Child's Nervous System Pub Date : 2024-12-01 Epub Date: 2024-09-30 DOI:10.1007/s00381-024-06635-x
Ingrid Maciel Barbosa, Alefe Luiz Gonçalves Rabelo, Edvaldo José Rodrigues Cardoso, Dyecika Souza Couto
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引用次数: 0

摘要

目的:这篇综合性文献综述旨在讨论利用胎盘作为病变部位的自体移植,通过产后手术矫正脊髓空洞症的益处和局限性;此外,它还试图强调胎盘的特性以及手术的益处和适应症:方法:本研究采用了 PRISMA 标准。于 2023 年 10 月 19 日使用 PubMed 作为数据库,并进行了三次检索,所有检索均使用 "脊髓膜膨出症 "和 "手术 "这两个词,仅在 "羊膜"、"胎盘 "和 "绒毛膜 "这三个词之间有所变化。共找到 91 篇文章,在对重复文章、纳入和排除标准进行分析后,只有 11 篇文章被用于本次系统性综述:结果:观察到羊膜的特性,如抗炎、刺激原生组织生长、分泌中性粒细胞因子的再生作用、促进上皮化、抑制纤维化和愈合以及抗菌作用。据观察,使用胎盘作为自体移植的益处与手术期之间存在矛盾:结论:胎盘具有加速愈合的特性,不会产生排斥反应,而且容易获取,因此越来越多的人选择自体移植。我们有信心说,羊膜的有效性是广泛可靠的。
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Placenta as a source of autologous graft in postnatal correction of myelomeningocele.

Objective: This integrative literature review aims to discuss the benefits and limitations of postnatal surgery to correct myelomeningocele using the placenta as an autologous graft used on the lesion; in addition, it seeks to highlight the placental properties and the benefits and indications of surgery.

Methods: For this production, the PRISMA criteria were used. PubMed was used as a database on October 19, 2023, and three searches were made, all using the words "myelomeningocele" and "surgery" varying only between "amnion," "placenta," and "chorion" as the third word. A total of 91 articles were found, and after analysis of duplicates and inclusion and exclusion criteria, only 11 articles were used in this systematic review.

Results: Properties of the amniotic membrane were observed, such as anti-inflammatory, stimulation of native tissue growth, regenerating action by the secretion of neutrophil factors, promotion of epithelialization, inhibition of fibrosis and healing, and antibacterial effect. It is observed that there are benefits in using the placenta as an autograft and there are contradictions between the periods of surgery.

Conclusion: Due to its properties that accelerate healing, the absence of the possibility of rejection, and its easy access make this choice more frequently adopted. We are confident in saying that the effectiveness of the amniotic membrane is widely reliable.

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来源期刊
Child's Nervous System
Child's Nervous System 医学-临床神经学
CiteScore
3.00
自引率
7.10%
发文量
322
审稿时长
3 months
期刊介绍: The journal has been expanded to encompass all aspects of pediatric neurosciences concerning the developmental and acquired abnormalities of the nervous system and its coverings, functional disorders, epilepsy, spasticity, basic and clinical neuro-oncology, rehabilitation and trauma. Global pediatric neurosurgery is an additional field of interest that will be considered for publication in the journal.
期刊最新文献
Correction: Imaging features of pediatric meningiomas: emphasis on unusual locations. Correction: Occipital encephalocele: a retrospective analysis and assessment of post-surgical neurodevelopmental outcome. Radiographic severity is associated with worse executive function in metopic craniosynostosis. Occipital encephalocele: a retrospective analysis and assessment of post-surgical neurodevelopmental outcome. Vaulting further: cranial vault expansion for craniocerebral disproportion without primary craniosynostosis.
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