{"title":"新生血管性年龄相关性黄斑变性静脉注射肉毒杆菌后的全厚黄斑孔。","authors":"Sang Hyeok Lee, Mee Yon Lee","doi":"10.1177/11206721241286708","DOIUrl":null,"url":null,"abstract":"<p><strong>Purpose: </strong>To describe a case of full thickness macular hole after intravitreal brolucizumab injection in neovascular age-related macular degeneration, which has not been reported to date.</p><p><strong>Case description: </strong>A 65-year-old male patient received brolucizumab intravitreal injection therapy for neovascular macular degeneration of the right eye. He received multiple intravitreal anti-VEGF injections on a pro re nata regimen and developed a full thickness macular hole.</p><p><strong>Outcome: </strong>Surgical treatment was performed with pars plana vitrectomy of the right eye. Full thickness macular hole was successfully treated.</p><p><strong>Conclusion: </strong>Although a full thickness macular hole following intravitreal brolucizumab injection is an uncommon complication, it requires caution.</p>","PeriodicalId":12000,"journal":{"name":"European Journal of Ophthalmology","volume":" ","pages":"NP16-NP19"},"PeriodicalIF":1.4000,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Full thickness macular hole after intravitreal brolucizumab injection in neovascular age-related macular degeneration.\",\"authors\":\"Sang Hyeok Lee, Mee Yon Lee\",\"doi\":\"10.1177/11206721241286708\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Purpose: </strong>To describe a case of full thickness macular hole after intravitreal brolucizumab injection in neovascular age-related macular degeneration, which has not been reported to date.</p><p><strong>Case description: </strong>A 65-year-old male patient received brolucizumab intravitreal injection therapy for neovascular macular degeneration of the right eye. He received multiple intravitreal anti-VEGF injections on a pro re nata regimen and developed a full thickness macular hole.</p><p><strong>Outcome: </strong>Surgical treatment was performed with pars plana vitrectomy of the right eye. Full thickness macular hole was successfully treated.</p><p><strong>Conclusion: </strong>Although a full thickness macular hole following intravitreal brolucizumab injection is an uncommon complication, it requires caution.</p>\",\"PeriodicalId\":12000,\"journal\":{\"name\":\"European Journal of Ophthalmology\",\"volume\":\" \",\"pages\":\"NP16-NP19\"},\"PeriodicalIF\":1.4000,\"publicationDate\":\"2025-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"European Journal of Ophthalmology\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1177/11206721241286708\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2024/9/27 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"Q3\",\"JCRName\":\"OPHTHALMOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"European Journal of Ophthalmology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1177/11206721241286708","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/9/27 0:00:00","PubModel":"Epub","JCR":"Q3","JCRName":"OPHTHALMOLOGY","Score":null,"Total":0}
Full thickness macular hole after intravitreal brolucizumab injection in neovascular age-related macular degeneration.
Purpose: To describe a case of full thickness macular hole after intravitreal brolucizumab injection in neovascular age-related macular degeneration, which has not been reported to date.
Case description: A 65-year-old male patient received brolucizumab intravitreal injection therapy for neovascular macular degeneration of the right eye. He received multiple intravitreal anti-VEGF injections on a pro re nata regimen and developed a full thickness macular hole.
Outcome: Surgical treatment was performed with pars plana vitrectomy of the right eye. Full thickness macular hole was successfully treated.
Conclusion: Although a full thickness macular hole following intravitreal brolucizumab injection is an uncommon complication, it requires caution.
期刊介绍：
The European Journal of Ophthalmology was founded in 1991 and is issued in print bi-monthly. It publishes only peer-reviewed original research reporting clinical observations and laboratory investigations with clinical relevance focusing on new diagnostic and surgical techniques, instrument and therapy updates, results of clinical trials and research findings.
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