前庭性偏头痛的现有和新兴治疗方案概览。

IF 3.4 2区 医学 Q2 CLINICAL NEUROLOGY Expert Review of Neurotherapeutics Pub Date : 2024-09-26 DOI:10.1080/14737175.2024.2405739
Elena P Calandre, Christine Bassila, Mahmoud Slim, Fernando Rico-Villademoros
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引用次数: 0

摘要

导言:前庭性偏头痛是一种比较常见的综合征,其特点是出现眩晕和其他前庭症状,经常(但并非总是)伴有偏头痛症状,如头痛、畏光和畏声:作者回顾了前庭性偏头痛发作时的急性或中止治疗以及预防性治疗,包括药物和非药物治疗方案:专家观点:由于前庭性偏头痛最近才被确认为一个独立的临床实体,因此有关其不同治疗方案的研究仍然很少,已发表研究的证据水平普遍较低。对于急性期的治疗,尽管现有的数据相互矛盾,但通常会首先试用三苯氧胺。神经刺激装置也可用于前庭性偏头痛的急性治疗。关于前庭性偏头痛的预防性治疗,根据两项随机临床试验的结果及其药理特性,氟桂利嗪应被视为首选治疗药物。二线预防性治疗包括普萘洛尔、托吡酯、文拉法辛和丙戊酸。在非药物治疗方案中,前庭康复似乎是一种不错的预防性治疗方案。
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An overview of the current and emerging treatment options for vestibular migraine.

Introduction: Vestibular migraine is a relatively common syndrome characterized by the occurrence of vertigo and other vestibular symptoms, frequently -but not always- accompanied by migraine symptoms, such as headache, photophobia, and phonophobia.

Areas covered: The authors review the acute or abortive treatment during an attack and prophylactic treatment of vestibular migraines, including pharmacological and non-pharmacological options.

Expert opinion: Since its recognition as an independent clinical entity is recent, studies concerning its different treatment alternatives are still scarce, and the level of evidence of published studies is generally low. For acute treatment, although available data are conflicting, triptans are usually tried first. Neurostimulating devices can also be considered for acute treatment of vestibular migraine. Regarding the preventive treatment of vestibular migraine, based on the results of two randomized clinical trials and its pharmacological properties, flunarizine should be considered as the first treatment option. Second-line preventive treatments encompass propranolol, topiramate, venlafaxine, and valproic acid. Among non-pharmacological options, vestibular rehabilitation seems to be a sound prophylactic treatment option.

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来源期刊
Expert Review of Neurotherapeutics
Expert Review of Neurotherapeutics Medicine-Neurology (clinical)
CiteScore
7.00
自引率
2.30%
发文量
61
审稿时长
4-8 weeks
期刊介绍: Expert Review of Neurotherapeutics (ISSN 1473-7175) provides expert reviews on the use of drugs and medicines in clinical neurology and neuropsychiatry. Coverage includes disease management, new medicines and drugs in neurology, therapeutic indications, diagnostics, medical treatment guidelines and neurological diseases such as stroke, epilepsy, Alzheimer''s and Parkinson''s. Comprehensive coverage in each review is complemented by the unique Expert Review format and includes the following sections: Expert Opinion - a personal view of the data presented in the article, a discussion on the developments that are likely to be important in the future, and the avenues of research likely to become exciting as further studies yield more detailed results Article Highlights – an executive summary of the author’s most critical points
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