使用细胞骨异体移植增量进行后足和踝关节置换术后的临床和影像学效果:简短报告。

Foot & Ankle Orthopaedics Pub Date : 2024-09-30 eCollection Date: 2024-07-01 DOI:10.1177/24730114241281325
Jeffrey R Ruland, Anna Sumpter, Eric McVey, Wendy Novicoff, Jennifer Pierce, Minton T Cooper, Venkat Perumal, Joseph S Park
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引用次数: 0

摘要

背景:踝关节或后足关节置换术后的不愈合与不良预后有关。细胞骨异体移植可替代自体移植用于此类手术。本研究的目的是对后足和踝关节置换术中使用细胞骨异体移植的早期疗效和安全性进行前瞻性评估:14名接受后足或踝关节置换术并辅以细胞骨异体移植的患者被纳入前瞻性研究。术后在设定的时间点进行计算机断层扫描(CT),并由 3 名受过研究培训的足踝外科医生和 1 名肌肉骨骼放射科医生进行复查。主要结果是经 CT 验证的结合,定义为关节表面>25%。对并发症进行记录,并根据情况提供翻修手术:研究期间,CT证实的结合率为76.7%(30个关节中的23个)。踝关节的结合率为100%(2例中的2例),距骨关节的结合率为50%(10例中的5例),方臼关节的结合率为100%(8例中的8例),距下关节的结合率为80.0%(10例中的8例)。研究期间,一名患者接受了翻修融合手术,一名患者接受了硬件移除手术:我们的初步经验表明,在后足和踝关节置换术中使用细胞骨同种异体移植增量可能是自体移植的一种替代方法,且不会造成供体部位的潜在发病率:证据等级:IV级,病例系列
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Clinical and Radiographic Outcomes After Hindfoot and Ankle Arthrodesis Using Cellular Bone Allograft Augmentation: A Short Report.

Background: Nonunion after ankle or hindfoot arthrodesis is associated with poor outcomes. Cellular bone allograft is an alternative to autograft for use in these procedures. The purpose of this study was to prospectively evaluate the early efficacy and safety of cellular bone allograft use in hindfoot and ankle arthrodesis procedures.

Methods: Fourteen patients undergoing hindfoot or ankle arthrodesis supplemented with cellular bone allograft were prospectively enrolled. Computed tomography (CT) scans were obtained postoperatively at set time points and reviewed by 3 fellowship-trained foot and ankle surgeons as well as 1 musculoskeletal radiologist. Primary outcome was CT-verified union, defined as >25% of joint surface. Complications were recorded and revision procedures offered as indicated.

Results: CT-verified union rate during the study period was 76.7% (23 of 30 joints). Union was 100% for the ankle joint (2 of 2), 50% for the talonavicular joint (5 of 10), 100% for the calcaneocuboid joint (8 of 8), and 80.0% for the subtalar joint (8 of 10). One patient underwent revision fusion procedure, and 1 patient underwent hardware removal during the study period.

Conclusion: Our initial experience suggests that use of cellular bone allograft augmentation in hindfoot and ankle arthrodesis may offer an alternative to autograft without potential of donor site morbidity.

Level of evidence: Level IV, case series.

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来源期刊
Foot & Ankle Orthopaedics
Foot & Ankle Orthopaedics Medicine-Orthopedics and Sports Medicine
CiteScore
1.20
自引率
0.00%
发文量
1152
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