用于癌症诊断和治疗的光声成像技术取得进展。

IF 5.3 2区 医学 Q1 PHARMACOLOGY & PHARMACY International Journal of Pharmaceutics Pub Date : 2024-09-24 DOI:10.1016/j.ijpharm.2024.124736
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引用次数: 0

摘要

光声成像可提供周围组织内肿瘤的活体形态和功能信息。通过整合超声引导,该技术可实现肿瘤的精确定位和特征描述。此外,靶向造影剂的引入进一步拓展了光声成像在体内分子成像领域的功能。这些造影剂有助于加强癌症的分子和细胞特征描述,使人们能够详细了解疾病。本综述旨在简明扼要地总结光声成像在癌症管理领域开展的广泛研究。它涵盖了该技术的发展、在临床环境中的应用以及在分子成像方面取得的进展。通过整合和归纳现有知识,本综述有助于更好地了解光声成像在癌症治疗中的潜力。总之,光声成像已成为一种非电离、非侵入性的成像方式,既能观察组织的光学吸收特性,又能保持超声的空间分辨率。它与靶向造影剂的结合增强了癌症的分子和细胞特征。本综述简明扼要地概述了该领域开展的广泛研究,揭示了光声成像在癌症治疗中的潜力。
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Advancements in photoacoustic imaging for cancer diagnosis and treatment
Photoacoustic imaging provides in vivo morphological and functional information about tumors within surrounding tissue. By integrating ultrasound guidance, this technique enables precise localization and characterization of tumors. Moreover, the introduction of targeted contrast agents has further expanded the capabilities of photoacoustic imaging in the realm of in vivo molecular imaging. These contrast agents facilitate enhanced molecular and cellular characterization of cancer, enabling detailed insights into the disease. This review aims to provide a concise summary of the extensive research conducted in the field of Photoacoustic imaging for cancer management. It encompasses the development of the technology, its applications in clinical settings, and the advancements made in molecular imaging. By consolidating and synthesizing the existing knowledge, this review contributes to a better understanding of the potential of photoacoustic imaging in cancer care. In conclusion, photoacoustic imaging has emerged as a non-ionizing and noninvasive modality with the ability to visualize tissue’s optical absorption properties while maintaining ultrasound’s spatial resolution. Its integration with targeted contrast agents has enhanced molecular and cellular characterization of cancer. This review serves as a succinct overview of the extensive research conducted in the field, shedding light on the potential of photoacoustic imaging in the management of cancer.
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来源期刊
CiteScore
10.70
自引率
8.60%
发文量
951
审稿时长
72 days
期刊介绍: The International Journal of Pharmaceutics is the third most cited journal in the "Pharmacy & Pharmacology" category out of 366 journals, being the true home for pharmaceutical scientists concerned with the physical, chemical and biological properties of devices and delivery systems for drugs, vaccines and biologicals, including their design, manufacture and evaluation. This includes evaluation of the properties of drugs, excipients such as surfactants and polymers and novel materials. The journal has special sections on pharmaceutical nanotechnology and personalized medicines, and publishes research papers, reviews, commentaries and letters to the editor as well as special issues.
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