Maciej Skrzypek, Rafał Kolec, Michał Słaboszewski, Katarzyna Góra, Agnieszka Olszanecka, Piotr Wróbel, Katarzyna Stolarz-Skrzypek, Marek W Rajzer
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We assessed carotid artery atherosclerotic plaques, along with carotid-femoral pulse wave velocity (cf-PWV) and left ventricular mass index (LVMI).</p><p><strong>Results: </strong>An equal to or higher than median (16 points) ODI score in 48 subjects (56.5%) was associated with the presence of carotid artery plaques (<i>p</i> = 0.014). In multivariate analysis, after adjusting for covariates, the presence of carotid artery plaques remained independently associated with an ODI score equal to or higher than the median (OR, 3.71; 95% CI, 1.04-13.25; <i>p</i> = 0.044). None of the other analyzed parameters of hypertension-related organ damage demonstrated a significant relationship with the ODI score.</p><p><strong>Conclusions: </strong>We observed that more severe cLBP is associated with a higher prevalence of carotid artery atherosclerotic plaques among hypertensive patients.</p>","PeriodicalId":15197,"journal":{"name":"Journal of Cardiovascular Development and Disease","volume":null,"pages":null},"PeriodicalIF":2.4000,"publicationDate":"2024-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11432398/pdf/","citationCount":"0","resultStr":"{\"title\":\"Hypertension-Mediated Organ Damage in Relation to Severity of Chronic Low Back Pain in Hypertensive Patients.\",\"authors\":\"Maciej Skrzypek, Rafał Kolec, Michał Słaboszewski, Katarzyna Góra, Agnieszka Olszanecka, Piotr Wróbel, Katarzyna Stolarz-Skrzypek, Marek W Rajzer\",\"doi\":\"10.3390/jcdd11090266\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Introduction: </strong>Chronic pain triggers a stress response, which results in increased blood pressure (BP). 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引用次数: 0
摘要
导言慢性疼痛会引发应激反应,导致血压(BP)升高。我们研究了高血压患者的慢性腰背痛(cLBP)是否与高血压相关器官损伤的风险增加有关:我们连续研究了 85 名患有慢性腰背痛的高血压患者,他们的中位年龄为 62 岁(55-67 岁)。患者接受了经胸超声心动图检查、动脉超声检查和血管测压。我们对颈动脉粥样硬化斑块、颈动脉-股动脉脉搏波速度(cf-PWV)和左心室质量指数(LVMI)进行了评估:48名受试者(56.5%)的ODI评分等于或高于中位数(16分)与颈动脉斑块的存在有关(p = 0.014)。在多变量分析中,调整协变量后,颈动脉斑块的存在仍与 ODI 评分等于或高于中位数独立相关(OR,3.71;95% CI,1.04-13.25;p = 0.044)。高血压相关器官损伤的其他分析参数均与 ODI 评分无显著关系:我们观察到,在高血压患者中,更严重的 cLBP 与更高的颈动脉粥样硬化斑块发病率有关。
Hypertension-Mediated Organ Damage in Relation to Severity of Chronic Low Back Pain in Hypertensive Patients.
Introduction: Chronic pain triggers a stress response, which results in increased blood pressure (BP). We investigated whether chronic low back pain (cLBP) in hypertensive patients is associated with an increased risk of hypertension-related organ damage.
Methods: We studied 85 consecutive hypertensive patients with a median age of 62 years (55-67), who suffered from cLBP, the severity of which was evaluated according to the Oswestry Disability Index (ODI). Patients underwent transthoracic echocardiography, arterial ultrasonography and vascular tonometry. We assessed carotid artery atherosclerotic plaques, along with carotid-femoral pulse wave velocity (cf-PWV) and left ventricular mass index (LVMI).
Results: An equal to or higher than median (16 points) ODI score in 48 subjects (56.5%) was associated with the presence of carotid artery plaques (p = 0.014). In multivariate analysis, after adjusting for covariates, the presence of carotid artery plaques remained independently associated with an ODI score equal to or higher than the median (OR, 3.71; 95% CI, 1.04-13.25; p = 0.044). None of the other analyzed parameters of hypertension-related organ damage demonstrated a significant relationship with the ODI score.
Conclusions: We observed that more severe cLBP is associated with a higher prevalence of carotid artery atherosclerotic plaques among hypertensive patients.