通过双面读取提高异质结构的计时性能。

IF 3.3 3区 医学 Q2 ENGINEERING, BIOMEDICAL Physics in medicine and biology Pub Date : 2024-10-08 DOI:10.1088/1361-6560/ad7fc8
Fiammetta Pagano, Nicolaus Kratochwil, Carsten Lowis, Woon-Seng Choong, Marco Paganoni, Marco Pizzichemi, Joshua W Cates, Etiennette Auffray
{"title":"通过双面读取提高异质结构的计时性能。","authors":"Fiammetta Pagano, Nicolaus Kratochwil, Carsten Lowis, Woon-Seng Choong, Marco Paganoni, Marco Pizzichemi, Joshua W Cates, Etiennette Auffray","doi":"10.1088/1361-6560/ad7fc8","DOIUrl":null,"url":null,"abstract":"<p><p><i>Objective.</i>Heterostructured scintillators offer a promising solution to balance the sensitivity and timing in TOF-PET detectors. These scintillators utilize alternating layers of materials with complementary properties to optimize performance. However, the layering compromises time resolution due to light transport issues. This study explores double-sided readout-enabling improved light collection and Depth-of-Interaction (DOI) information retrieval-to mitigate this effect and enhance the timing capabilities of heterostructures.<i>Approach.</i>The time resolution and DOI performances of 3 × 3 × 20 mm<sup>3</sup>BGO&EJ232 heterostructures were assessed in a single and double-sided readout (SSR and DSR, respectively) configuration using high-frequency electronics.<i>Main results.</i>Selective analysis of photopeak events yielded a DOI resolution of 6.4 ± 0.04 mm. Notably, the Coincidence Time Resolution (CTR) improved from 262 ± 8 ps (SSR) to 174 ± 6 ps (DSR) when measured in coincidence with a fast reference detector. Additionally, symmetrical configuration of two identical heterostructures in coincidence was tested, yielding in DSR a CTR of 254 ± 8 ps for all photopeak events and 107 ± 5 ps for the fastest events.<i>Significance.</i>By using high-frequency double-sided readout, we could measure DOI resolution and improve the time resolution of heterostructures of up to 40%. The DOI information resulted intrinsically captured in the average between the timestamps of the two SiPMs, without requiring any further correction.</p>","PeriodicalId":20185,"journal":{"name":"Physics in medicine and biology","volume":null,"pages":null},"PeriodicalIF":3.3000,"publicationDate":"2024-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Enhancing timing performance of heterostructures with double-sided readout.\",\"authors\":\"Fiammetta Pagano, Nicolaus Kratochwil, Carsten Lowis, Woon-Seng Choong, Marco Paganoni, Marco Pizzichemi, Joshua W Cates, Etiennette Auffray\",\"doi\":\"10.1088/1361-6560/ad7fc8\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p><i>Objective.</i>Heterostructured scintillators offer a promising solution to balance the sensitivity and timing in TOF-PET detectors. These scintillators utilize alternating layers of materials with complementary properties to optimize performance. However, the layering compromises time resolution due to light transport issues. This study explores double-sided readout-enabling improved light collection and Depth-of-Interaction (DOI) information retrieval-to mitigate this effect and enhance the timing capabilities of heterostructures.<i>Approach.</i>The time resolution and DOI performances of 3 × 3 × 20 mm<sup>3</sup>BGO&EJ232 heterostructures were assessed in a single and double-sided readout (SSR and DSR, respectively) configuration using high-frequency electronics.<i>Main results.</i>Selective analysis of photopeak events yielded a DOI resolution of 6.4 ± 0.04 mm. Notably, the Coincidence Time Resolution (CTR) improved from 262 ± 8 ps (SSR) to 174 ± 6 ps (DSR) when measured in coincidence with a fast reference detector. Additionally, symmetrical configuration of two identical heterostructures in coincidence was tested, yielding in DSR a CTR of 254 ± 8 ps for all photopeak events and 107 ± 5 ps for the fastest events.<i>Significance.</i>By using high-frequency double-sided readout, we could measure DOI resolution and improve the time resolution of heterostructures of up to 40%. The DOI information resulted intrinsically captured in the average between the timestamps of the two SiPMs, without requiring any further correction.</p>\",\"PeriodicalId\":20185,\"journal\":{\"name\":\"Physics in medicine and biology\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":3.3000,\"publicationDate\":\"2024-10-08\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Physics in medicine and biology\",\"FirstCategoryId\":\"5\",\"ListUrlMain\":\"https://doi.org/10.1088/1361-6560/ad7fc8\",\"RegionNum\":3,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"ENGINEERING, BIOMEDICAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Physics in medicine and biology","FirstCategoryId":"5","ListUrlMain":"https://doi.org/10.1088/1361-6560/ad7fc8","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"ENGINEERING, BIOMEDICAL","Score":null,"Total":0}
引用次数: 0

摘要

异质结构闪烁体为平衡 TOF-PET 探测器的灵敏度和定时提供了一种很有前景的解决方案。这些闪烁体利用具有互补特性的交替材料层来优化性能。然而,由于光传输问题,分层会影响时间分辨率。本研究探讨了双面读出(可改善光收集和相互作用深度(DOI)信息检索),以减轻这种影响并增强异质结构的计时能力。对光峰事件的选择性分析得出的 DOI 分辨率为 6.4x0.04mm。值得注意的是,在与快速参考探测器重合测量时,重合时间分辨率(CTR)从 262±8 ps(SSR)提高到 174±6 ps(DSR)。此外,我们还测试了两个完全相同的异质结构的对称配置,在 DSR 中,所有光峰事件的 CTR 为 254±8 ps,最快事件的 CTR 为 107±5 ps。DOI 信息从两个 SiPM 的时间戳平均值中获得,无需进一步校正。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
Enhancing timing performance of heterostructures with double-sided readout.

Objective.Heterostructured scintillators offer a promising solution to balance the sensitivity and timing in TOF-PET detectors. These scintillators utilize alternating layers of materials with complementary properties to optimize performance. However, the layering compromises time resolution due to light transport issues. This study explores double-sided readout-enabling improved light collection and Depth-of-Interaction (DOI) information retrieval-to mitigate this effect and enhance the timing capabilities of heterostructures.Approach.The time resolution and DOI performances of 3 × 3 × 20 mm3BGO&EJ232 heterostructures were assessed in a single and double-sided readout (SSR and DSR, respectively) configuration using high-frequency electronics.Main results.Selective analysis of photopeak events yielded a DOI resolution of 6.4 ± 0.04 mm. Notably, the Coincidence Time Resolution (CTR) improved from 262 ± 8 ps (SSR) to 174 ± 6 ps (DSR) when measured in coincidence with a fast reference detector. Additionally, symmetrical configuration of two identical heterostructures in coincidence was tested, yielding in DSR a CTR of 254 ± 8 ps for all photopeak events and 107 ± 5 ps for the fastest events.Significance.By using high-frequency double-sided readout, we could measure DOI resolution and improve the time resolution of heterostructures of up to 40%. The DOI information resulted intrinsically captured in the average between the timestamps of the two SiPMs, without requiring any further correction.

求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
Physics in medicine and biology
Physics in medicine and biology 医学-工程:生物医学
CiteScore
6.50
自引率
14.30%
发文量
409
审稿时长
2 months
期刊介绍: The development and application of theoretical, computational and experimental physics to medicine, physiology and biology. Topics covered are: therapy physics (including ionizing and non-ionizing radiation); biomedical imaging (e.g. x-ray, magnetic resonance, ultrasound, optical and nuclear imaging); image-guided interventions; image reconstruction and analysis (including kinetic modelling); artificial intelligence in biomedical physics and analysis; nanoparticles in imaging and therapy; radiobiology; radiation protection and patient dose monitoring; radiation dosimetry
期刊最新文献
Noise & mottle suppression methods for cumulative Cherenkov images of radiation therapy delivery. Quantitative assessment of areal bone mineral density using multi-energy localizer radiographs from photon-counting detector CT. TMAA-net: tensor-domain multi-planal anti-aliasing network for sparse-view CT image reconstruction. Imaging error reduction in radial cine-MRI with deep learning-based intra-frame motion compensation. Investigation of scatter energy window width and count levels for deep learning-based attenuation map estimation in cardiac SPECT/CT imaging.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1