Chris B Lamprecht, Abeer Dagra, Brandon Lucke-Wold
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引用次数: 0
摘要
谵妄是一种复杂的神经认知综合征,经常在手术后出现,表现形式多种多样,且存在相当大的障碍,尤其是在老年人中。这篇社论深入探讨了术后谵妄(POD)这一错综复杂的现象,阐明了一项探讨接受腹部恶性肿瘤手术的老年人术后谵妄的研究。该研究探讨了病理生理学和预测性决定因素,为这一具有挑战性的临床情况提供了宝贵的见解。该研究采用了合成少数超采样技术,建立了一个预测模型,其中纳入了合并症指数、麻醉等级和手术持续时间等关键风险因素。目前迫切需要准确识别风险因素,以降低 POD 发生率。这些研究结果虽然只针对腹部恶性肿瘤老年患者,但对了解谵妄的病理生理学和预测有很大帮助。我们有必要开展进一步研究,建立标准化的预测方法,以增强其通用性。
Predictive modeling for post operative delirium in elderly.
Delirium, a complex neurocognitive syndrome, frequently emerges following surgery, presenting diverse manifestations and considerable obstacles, especially among the elderly. This editorial delves into the intricate phenomenon of postoperative delirium (POD), shedding light on a study that explores POD in elderly individuals undergoing abdominal malignancy surgery. The study examines pathophysiology and predictive determinants, offering valuable insights into this challenging clinical scenario. Employing the synthetic minority oversampling technique, a predictive model is developed, incorporating critical risk factors such as comorbidity index, anesthesia grade, and surgical duration. There is an urgent need for accurate risk factor identification to mitigate POD incidence. While specific to elderly patients with abdominal malignancies, the findings contribute significantly to understanding delirium pathophysiology and prediction. Further research is warranted to establish standardized predictive for enhanced generalizability.
期刊介绍:
The World Journal of Gastrointestinal Oncology (WJGO) is a leading academic journal devoted to reporting the latest, cutting-edge research progress and findings of basic research and clinical practice in the field of gastrointestinal oncology.