Dominik L Reinhard, Anna Schmidt, Marc Sons, Julian Wolf, Elric Engelage, Stefan M Huber
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引用次数: 0
摘要
近年来,二碘鎓(III)盐已被确定为强大的卤素键供体。在此,我们为这一类化合物开发了一种新的结构模式:碘异噁唑鎓盐,其环状五元碘核心与异噁唑环融合。合成了这一类化合物的衍生物,并通过 X 射线晶体学对其固态进行了研究。最后,在金催化丙炔酰胺环化的溶液中,对其作为卤素键活化剂的潜力进行了基准测试。
Evaluating the halogen bonding strength of a iodoloisoxazolium(III) salt.
Diaryliodonium(III) salts have been established as powerful halogen-bond donors in recent years. Herein, a new structural motif for this compound class was developed: iodoloisoxazolium salts, bearing a cyclic five-membered iodolium core fused with an isoxazole ring. A derivative of this class was synthesized and investigated in the solid state by X-ray crystallography. Finally, the potential as halogen-bonding activator was benchmarked in solution in the gold-catalyzed cyclization of a propargyl amide.
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