一名高安动脉炎患者的多发性硬化症：病例报告。

Pub Date : 2024-09-07 eCollection Date: 2024-01-01 DOI:10.22088/cjim.15.4.729

Mohammad Mehdi Emam, Mahdiye Abiyarghamsari, Muhanna Kazempour, Maryam Haghighi-Morad, Farane Farsad

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摘要

背景：多发性硬化症（MS）和高安氏动脉炎（TAK）是影响中枢神经系统（CNS）的两种自身免疫性疾病，但它们之间的关系尚未确定：我们在此报告在治疗过程中出现的多发性硬化症。病例介绍：我们在此报告了一名 24 岁伊朗女性在治疗过程中出现的 MS。她接受了为期 3 天、每天 1 克甲基强的松龙静脉注射的积极治疗，并继续口服强的松龙，同时每月静脉注射环磷酰胺。2 个月后，由于视力下降，她被诊断为多发性硬化症并发的视神经炎（ON）：结论：将与高安关节炎相关的中枢神经系统血管炎与并存的影响中枢神经系统的多发性硬化症区分开来具有挑战性，重要的是避免使用 TNF 抑制剂。

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Multiple sclerosis in a patient with Takayasu's Arteritis: A case report.

Background: Multiple sclerosis (MS) and Takayasu's arteritis (TAK) are two autoimmune diseases that affect the Central nervous system (CNS), but the relationship between them has not been established.

Case presentation: Here we report the emergence of MS during treatment. Takayasu's arteritis in a 24-year-old Iranian woman with a severe presentation. She was treated aggressively with IV methylprednisolone 1 g/day for 3 days and continued with oral prednisolone, also IV cyclophosphamide monthly. After 2 months, loss of vision led to a diagnosis of Optic neuritis (ON) caused by concomitant MS.

Conclusion: Differentiating CNS vasculitis associated with Takayasu's arthritis from coexisting MS affecting the CNS is challenging and what is important is to avoid giving a TNF inhibitor.

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