{"title":"冷冻电镜与 X 病症","authors":"Fasséli Coulibaly","doi":"10.1016/j.cell.2024.09.002","DOIUrl":null,"url":null,"abstract":"In this issue of <em>Cell</em>, Penzes et al. describe the use of cryo-EM to identify the cause of a mysterious disease affecting farmed superworms across the US. The study illustrates the power of <em>ex vivo</em> cryo-EM, which uses amplification-free samples to advance at once diagnostic, DNA packaging mechanism, and preventative measures.","PeriodicalId":9656,"journal":{"name":"Cell","volume":null,"pages":null},"PeriodicalIF":45.5000,"publicationDate":"2024-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Cryo-EM vs. Disease X\",\"authors\":\"Fasséli Coulibaly\",\"doi\":\"10.1016/j.cell.2024.09.002\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"In this issue of <em>Cell</em>, Penzes et al. describe the use of cryo-EM to identify the cause of a mysterious disease affecting farmed superworms across the US. The study illustrates the power of <em>ex vivo</em> cryo-EM, which uses amplification-free samples to advance at once diagnostic, DNA packaging mechanism, and preventative measures.\",\"PeriodicalId\":9656,\"journal\":{\"name\":\"Cell\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":45.5000,\"publicationDate\":\"2024-10-03\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Cell\",\"FirstCategoryId\":\"99\",\"ListUrlMain\":\"https://doi.org/10.1016/j.cell.2024.09.002\",\"RegionNum\":1,\"RegionCategory\":\"生物学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"BIOCHEMISTRY & MOLECULAR BIOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Cell","FirstCategoryId":"99","ListUrlMain":"https://doi.org/10.1016/j.cell.2024.09.002","RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"BIOCHEMISTRY & MOLECULAR BIOLOGY","Score":null,"Total":0}
In this issue of Cell, Penzes et al. describe the use of cryo-EM to identify the cause of a mysterious disease affecting farmed superworms across the US. The study illustrates the power of ex vivo cryo-EM, which uses amplification-free samples to advance at once diagnostic, DNA packaging mechanism, and preventative measures.
期刊介绍：
Cells is an international, peer-reviewed, open access journal that focuses on cell biology, molecular biology, and biophysics. It is affiliated with several societies, including the Spanish Society for Biochemistry and Molecular Biology (SEBBM), Nordic Autophagy Society (NAS), Spanish Society of Hematology and Hemotherapy (SEHH), and Society for Regenerative Medicine (Russian Federation) (RPO).
The journal publishes research findings of significant importance in various areas of experimental biology, such as cell biology, molecular biology, neuroscience, immunology, virology, microbiology, cancer, human genetics, systems biology, signaling, and disease mechanisms and therapeutics. The primary criterion for considering papers is whether the results contribute to significant conceptual advances or raise thought-provoking questions and hypotheses related to interesting and important biological inquiries.
In addition to primary research articles presented in four formats, Cells also features review and opinion articles in its "leading edge" section, discussing recent research advancements and topics of interest to its wide readership.
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