基于血红素的水生受体

Q3 Medicine Postepy biochemii Pub Date : 2024-09-17 Print Date: 2024-09-30 DOI:10.18388/pb.2021_551
Savani Anbalagan
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引用次数: 0

摘要

细胞如何感知水分在生物学中至关重要。特化的感觉细胞能感知细胞外的水分,这一点已在它们身上得到证实。即使在微生物中,渗透传感器本身也不能感知水分。水感应机制是生物在缺水条件下迁移和生存以及进化成多细胞生物的必要条件。由于水分子有可能与气体感受器基于血红素的感应结构域中的气体结合位点结合,我认为它们中的一些可能具有与蛋白质水感受器平行的作用。正如气体感受器在几乎所有细胞中都起作用一样,水感受器也一定在几乎所有细胞中都起作用。我认为,细胞膜、细胞质和细胞器中一定都有水感受器。我还想知道血红蛋白是否也可以被视为一种潜在的水感受器。
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Heme-based aquareceptors

How cells sense water is of fundamental importance in biology. Hygrosensation has been demonstrated in specialized sensory cells that sense extracellular moisture. Even in microorganisms, osmosensors do not sense water per se. Water-sensing mechanisms would have been necessary for organisms to migrate and survive in water-poor conditions and to evolve into multicellular organisms. Due to the potential ability of water molecules to bind to gas-binding sites in the heme-based sensing domains of gasoreceptors, I suggest that some of them could have a parallel role as protein aquareceptors. Just as gasoreceptors function in almost every cell, aquareceptors must also function in almost every cell. I think that aquareceptors must be present in the cell membrane, cytoplasm, and every organelle. I also wonder if hemoglobin could also be considered a putative aquareceptor.

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Postepy biochemii
Postepy biochemii Medicine-Medicine (all)
CiteScore
0.80
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0.00%
发文量
36
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