{"title":"超声波检查中通过骨皮质的血流信号可用作筛查检测早期膝骨关节炎患者磁共振成像中的骨髓病变。","authors":"Naoki Takemoto, Yasushi Takata, Yosuke Shima, Kenichi Goshima, Kengo Shimozaki, Mitsuhiro Kimura, Tomoyuki Kanayama, Satoru Demura, Junsuke Nakase","doi":"10.1007/s10396-024-01503-2","DOIUrl":null,"url":null,"abstract":"<p><strong>Purpose: </strong>Blood flow signals (BFSs) through the bone cortex on ultrasonography (US) and bone marrow lesions (BMLs) detected on magnetic resonance imaging (MRI) can be used to assess bone lesions; however, no studies have reported their relationship. Therefore, this study aimed to assess whether BFSs through the bone cortex on US can serve as a screening test for detecting BMLs on MRI in patients with early knee osteoarthritis (OA).</p><p><strong>Methods: </strong>This study enrolled patients with knee joint pain who were diagnosed with early knee OA between January 2018 and January 2024. We targeted 77 patients who underwent MRI and in whom the presence or absence of BFSs through the bone cortex was confirmed on US. The association between BFSs and BMLs was evaluated using the chi-square test, and the sensitivity and specificity of BFSs for detecting BMLs on MRI were calculated.</p><p><strong>Results: </strong>The chi-square test showed that BFSs and BMLs were significantly associated in the femur and tibia (femur: χ<sup>2</sup> [1] = 52.9, p < 0.001; Tibia: χ<sup>2</sup> [1] = 44.8, p < 0.001). The sensitivity, specificity, positive predictive value, and negative predictive value of BFSs for detecting BMLs on MRI were 85.0%, 96.5%, 89.5%, and 94.8%, respectively, for the femur, and 84.0%, 92.3%, 84.0%, and 92.3%, respectively, for the tibia.</p><p><strong>Conclusion: </strong>BFSs through the bone cortex on US can be used as a screening test for detecting BMLs on MRI in patients with early knee OA.</p>","PeriodicalId":50130,"journal":{"name":"Journal of Medical Ultrasonics","volume":null,"pages":null},"PeriodicalIF":1.9000,"publicationDate":"2024-10-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Blood flow signals through the bone cortex on ultrasonography can be used as a screening test for detecting bone marrow lesions on magnetic resonance imaging in patients with early knee osteoarthritis.\",\"authors\":\"Naoki Takemoto, Yasushi Takata, Yosuke Shima, Kenichi Goshima, Kengo Shimozaki, Mitsuhiro Kimura, Tomoyuki Kanayama, Satoru Demura, Junsuke Nakase\",\"doi\":\"10.1007/s10396-024-01503-2\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Purpose: </strong>Blood flow signals (BFSs) through the bone cortex on ultrasonography (US) and bone marrow lesions (BMLs) detected on magnetic resonance imaging (MRI) can be used to assess bone lesions; however, no studies have reported their relationship. Therefore, this study aimed to assess whether BFSs through the bone cortex on US can serve as a screening test for detecting BMLs on MRI in patients with early knee osteoarthritis (OA).</p><p><strong>Methods: </strong>This study enrolled patients with knee joint pain who were diagnosed with early knee OA between January 2018 and January 2024. We targeted 77 patients who underwent MRI and in whom the presence or absence of BFSs through the bone cortex was confirmed on US. The association between BFSs and BMLs was evaluated using the chi-square test, and the sensitivity and specificity of BFSs for detecting BMLs on MRI were calculated.</p><p><strong>Results: </strong>The chi-square test showed that BFSs and BMLs were significantly associated in the femur and tibia (femur: χ<sup>2</sup> [1] = 52.9, p < 0.001; Tibia: χ<sup>2</sup> [1] = 44.8, p < 0.001). The sensitivity, specificity, positive predictive value, and negative predictive value of BFSs for detecting BMLs on MRI were 85.0%, 96.5%, 89.5%, and 94.8%, respectively, for the femur, and 84.0%, 92.3%, 84.0%, and 92.3%, respectively, for the tibia.</p><p><strong>Conclusion: </strong>BFSs through the bone cortex on US can be used as a screening test for detecting BMLs on MRI in patients with early knee OA.</p>\",\"PeriodicalId\":50130,\"journal\":{\"name\":\"Journal of Medical Ultrasonics\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":1.9000,\"publicationDate\":\"2024-10-04\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Medical Ultrasonics\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1007/s10396-024-01503-2\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Medical Ultrasonics","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1007/s10396-024-01503-2","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING","Score":null,"Total":0}
引用次数: 0
摘要
目的：超声波成像（US）上通过骨皮质的血流信号（BFSs）和磁共振成像（MRI）上检测到的骨髓病变（BMLs）可用于评估骨病变；然而，还没有研究报告它们之间的关系。因此，本研究旨在评估 US 上穿过骨皮质的 BFS 是否可作为早期膝关节骨性关节炎（OA）患者 MRI 上检测 BML 的筛选测试：本研究招募了2018年1月至2024年1月期间被诊断为早期膝关节OA的膝关节疼痛患者。我们的研究对象是 77 名接受 MRI 检查的患者，这些患者经 US 证实存在或不存在穿过骨皮质的 BFS。采用卡方检验评估了BFS与BML之间的关联，并计算了BFS在MRI上检测BML的敏感性和特异性：US 上穿过骨皮质的 BFS 可作为早期膝关节 OA 患者 MRI 上检测 BML 的筛选测试。
Blood flow signals through the bone cortex on ultrasonography can be used as a screening test for detecting bone marrow lesions on magnetic resonance imaging in patients with early knee osteoarthritis.
Purpose: Blood flow signals (BFSs) through the bone cortex on ultrasonography (US) and bone marrow lesions (BMLs) detected on magnetic resonance imaging (MRI) can be used to assess bone lesions; however, no studies have reported their relationship. Therefore, this study aimed to assess whether BFSs through the bone cortex on US can serve as a screening test for detecting BMLs on MRI in patients with early knee osteoarthritis (OA).
Methods: This study enrolled patients with knee joint pain who were diagnosed with early knee OA between January 2018 and January 2024. We targeted 77 patients who underwent MRI and in whom the presence or absence of BFSs through the bone cortex was confirmed on US. The association between BFSs and BMLs was evaluated using the chi-square test, and the sensitivity and specificity of BFSs for detecting BMLs on MRI were calculated.
Results: The chi-square test showed that BFSs and BMLs were significantly associated in the femur and tibia (femur: χ2 [1] = 52.9, p < 0.001; Tibia: χ2 [1] = 44.8, p < 0.001). The sensitivity, specificity, positive predictive value, and negative predictive value of BFSs for detecting BMLs on MRI were 85.0%, 96.5%, 89.5%, and 94.8%, respectively, for the femur, and 84.0%, 92.3%, 84.0%, and 92.3%, respectively, for the tibia.
Conclusion: BFSs through the bone cortex on US can be used as a screening test for detecting BMLs on MRI in patients with early knee OA.
期刊介绍：
The Journal of Medical Ultrasonics is the official journal of the Japan Society of Ultrasonics in Medicine. The main purpose of the journal is to provide forum for the publication of papers documenting recent advances and new developments in the entire field of ultrasound in medicine and biology, encompassing both the medical and the engineering aspects of the science.The journal welcomes original articles, review articles, images, and letters to the editor.The journal also provides state-of-the-art information such as announcements from the boards and the committees of the society.
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