疑似川崎病成人患者的 "无触点 "隐静脉移植术和冠状动脉瘤结扎术

IF 16.4 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY Accounts of Chemical Research Pub Date : 2024-10-06 DOI:10.12659/AJCR.945431
Satoshi Ueno, Yuji Katayama, Takashi Kudo, Naomi Nishikawa, Yoshiro Nagao, Hideki Shimomura
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引用次数: 0

摘要

背景 川崎病患者的冠状动脉动脉瘤可能引发急性心肌梗死。对这些患者来说,仅通过经皮冠状动脉介入治疗实现完全血管再通具有挑战性。因此,通常需要进行冠状动脉搭桥术。病例报告 我们报告了一例 68 岁女性患者的病例,她因右冠状动脉(RCA)和左侧环状动脉(LCx)形成的巨大动脉瘤而导致多次急性心肌梗死。根据冠状动脉造影、化验结果和家族病史,我们诊断动脉瘤的病因为川崎病。在初级球囊血管成形术后,我们进行了冠状动脉旁路移植术,其中包括向 LCx 移植 2 根血管,向 RCA 移植 1 根血管。胸内动脉是标准的移植血管,但很可能因川崎病血管炎而闭塞。因此,我们使用了通过 "无接触 "技术采集的大隐静脉移植物,该技术保留了血管周围的脂肪组织,从而提高了长期的通畅性。此外,我们还结扎了 LCx 动脉瘤,以防止移植物闭塞和动脉瘤破裂。顺利出院四年后,患者健康状况良好,冠状动脉计算机断层扫描血管造影显示所有移植物的通畅性良好。结论 本报告重点介绍了在一名川崎病成年患者身上成功结合使用 "无接触 "大隐静脉移植术和冠状动脉瘤结扎术的情况。这些技术可能对这种经常伴有胸内动脉闭塞的血管性疾病特别有用。
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"No-Touch" Saphenous Vein Grafting and Coronary Aneurysm Ligation in an Adult Patient with Suspected Prior Kawasaki Disease.

BACKGROUND Coronary artery aneurysms in patients with Kawasaki disease may develop acute myocardial infarction. It is challenging to achieve complete revascularization solely through percutaneous coronary intervention in these patients. Therefore, coronary artery bypass grafting is often necessary. CASE REPORT We present a case of a 68-year-old woman who developed multiple acute myocardial infarctions due to giant aneurysms formed in the right coronary artery (RCA) and the left circumflex artery (LCx). We diagnosed the cause of the aneurysms as Kawasaki disease based on the coronary angiogram, laboratory results, and family history. After the primary balloon angioplasty, we conducted coronary artery bypass grafting, which involved grafting 2 vessels to the LCx and 1 vessel to the RCA. The internal thoracic arteries, which are the standard graft vessels, were occluded, most likely due to Kawasaki disease vasculitis. Instead, we used saphenous vein grafts harvested using the "no-touch" technique, which preserves the perivascular adipose tissue, to improve the long-term patency. In addition, we ligated the LCx aneurysm to prevent occlusion of the grafts and rupture of the aneurysm. Four years after the uneventful discharge, the patient is in good health and coronary computed tomography angiography revealed good patency of all grafts. CONCLUSIONS This report highlights a successful combination of "no-touch" saphenous vein grafting and coronary aneurysm ligation in an adult patient with Kawasaki disease. These techniques may be especially useful for this vasculitic illness which is often associated with occlusion of internal thoracic arteries.

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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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