临终肺癌患者抗癌药物使用情况的范围审查。

IF 2.8 3区 医学 Q2 ONCOLOGY Clinical & Translational Oncology Pub Date : 2024-10-05 DOI:10.1007/s12094-024-03711-1
Endre Szigethy, Mohammed Merzah, Ivan Sola, Gerard Urrútia, Xavier Bonfill
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引用次数: 0

摘要

目的:本综述旨在加深对肺癌患者临终前抗癌药物使用情况的了解,肺癌是一种死亡率和症状负担都很高的疾病。洞察独特的临终治疗模式对于提高这些患者癌症治疗的适当性至关重要:方法:我们在 Medline 和 Embase 中进行了全面检索,以找到有关肺癌患者临终前使用抗癌药物的文章:我们确定了 68 篇文献,重点介绍了研究方法的特点,包括研究时间、疾病状况、治疗方案、治疗类型和治疗特点。我们概述了不同生命末期抗癌药物的使用频率:本综述全面概述了探讨肺癌患者临终治疗的主要研究。方法上的不一致带来了许多挑战,揭示了潜在过度治疗患者的显著比例,需要更标准化的研究方法来进行稳健的评估。
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Scoping review of anticancer drug utilization in lung cancer patients at the end of life.

Purpose: This scoping review aims to deepen the understanding of end-of-life anticancer drug use in lung cancer patients, a disease marked by high mortality and symptom burden. Insight into unique end-of-life treatment patterns is crucial for improving the appropriateness of cancer care for these patients.

Methods: Comprehensive searches were carried out in Medline and Embase to find articles on the utilization of anticancer drugs in the end of life of lung cancer patients.

Results: We identified 68 publications, highlighting the methodological characteristics of studies including the timing of the research, disease condition, treatment regimen, type of treatment, and features of the treatment. We outlined the frequency of anticancer drug use throughout different end-of-life periods.

Conclusion: This review provides a comprehensive overview of primary studies exploring end-of-life treatments in lung cancer patients. Methodological inconsistencies pose many challenges, revealing a notable proportion of patients experiencing potential overtreatment, warranting more standardized research methods for robust evaluations.

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来源期刊
CiteScore
6.20
自引率
2.90%
发文量
240
审稿时长
1 months
期刊介绍: Clinical and Translational Oncology is an international journal devoted to fostering interaction between experimental and clinical oncology. It covers all aspects of research on cancer, from the more basic discoveries dealing with both cell and molecular biology of tumour cells, to the most advanced clinical assays of conventional and new drugs. In addition, the journal has a strong commitment to facilitating the transfer of knowledge from the basic laboratory to the clinical practice, with the publication of educational series devoted to closing the gap between molecular and clinical oncologists. Molecular biology of tumours, identification of new targets for cancer therapy, and new technologies for research and treatment of cancer are the major themes covered by the educational series. Full research articles on a broad spectrum of subjects, including the molecular and cellular bases of disease, aetiology, pathophysiology, pathology, epidemiology, clinical features, and the diagnosis, prognosis and treatment of cancer, will be considered for publication.
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