EMVision:用于准确放置间质近距离放射治疗应用器的电磁跟踪引导系统。

Christopher L Deufel, Eric E Brost, Justine M Dupere, Ivy A Petersen, Michael G Haddock, Allison E Garda
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摘要

目的:设计、构建并评估一套利用电磁追踪(EMT)技术在图像引导下放置近距离放射治疗应用器的系统,以提高手术质量和效率。该系统被命名为 EMVision,可提供计划置针部位的三维显示、置针过程中解剖结构和置针位置的可视性,以及考虑到发生器或目标解剖结构移动的参考跟踪:方法:EMVision EMT 引导系统使用基于点的自动算法,根据串联/卵巢位置注册 CT 和 EMT 参考框架。随后通过腔内 EMT 传感器和用户界面引导穿刺针的放置和数字化,用户界面可在轴向、冠状、矢状和三维容积 CT 视图中显示穿刺针的位置。该界面可以叠加轮廓、预先计划的针头,并在置针/操作过程中为串联运动提供 6DOF 补偿。通过比较 EMVision 的 DICOM 针位置和地面实况、植入后 CT,在模型和人体尸体中评估了 EMVision 的准确性:结果:EMT 辅助近距离放射治疗针置入的概念得到验证。EMVision在模型(平均值±标准偏差)上的近距治疗CT台上的精确度为:针尖距离串联体/假体75毫米以内的精确度为0.76±0.13毫米,针轴距离串联体/假体100毫米以内的精确度为0.52±0.27毫米。在人体尸体上的表现类似,针尖和针杆的精确度分别为 0.77 ± 0.14 毫米和 0.40 ± 0.21 毫米:结论:EMVision 可提供亚毫米级的近距治疗针置放精度,无需重复或连续成像。该技术可用于缩短近距离治疗手术时间,提高预期针头位置与实际针头位置之间的对应性,或降低受训者的学习曲线。
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EMVision: An electromagnetic tracking guidance system for accurate placement of interstitial brachytherapy applicators.

Purpose: To design, construct, and evaluate a system for image-guided placement of brachytherapy applicators using electromagnetic tracking (EMT) technology for improved procedure quality and efficiency. The system, named EMVision, provides a three-dimensional display of planned needle sites, visibility of the anatomy and needle position during placement, and reference tracking to account for generator or target anatomy shifts.

Methods: The EMVision EMT guidance system registers CT and EMT reference frames using an automated point-based algorithm according to tandem/ovoid locations. Subsequent needle placement and digitization is guided with an intraluminal EMT sensor and user interface that displays the needle's location in axial, coronal, sagittal, and 3D-volumetric CT views. The interface can overlay contours, preplanned needles, and provide 6DOF compensation for tandem movement during needle placement/manipulation. EMVision accuracy was evaluated in phantom and human cadaver by comparing EMVision's DICOM needle positions with a ground-truth, postimplant CT.

Results: Proof of concept was demonstrated for EMT-assisted placement of brachytherapy needles. EMVision accuracy in phantom (mean ± standard deviation) on a brachysuite CT table was 0.76 ± 0.13 mm for needle tips placed up to 75 mm from the tandem/ovoids and 0.52 ± 0.27 mm for needle shafts at distances up to 100 mm from the tandem/ovoids. Performance in human cadaver was similar, with tip and shaft accuracies of 0.77 ± 0.14 mm and 0.40 ± 0.21 mm, respectively.

Conclusion: EMVision provides sub-millimeter accuracy for the placement of brachytherapy needles without repeated or continuous imaging. The technology can be used to reduce brachytherapy procedure times, improve the correspondence between intended and actual needle positions, or decrease the trainee learning curve.

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