建立上肢移植项目:12 年来的经验教训。

IF 1.8 4区 医学 Q3 TRANSPLANTATION Current Opinion in Organ Transplantation Pub Date : 2024-12-01 Epub Date: 2024-10-04 DOI:10.1097/MOT.0000000000001181
Kevin J Zuo, Alessandra Zaccardelli, Simon G Talbot
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引用次数: 0

摘要

回顾的目的:作为世界上早期的手移植项目之一,我们经常被要求向其他项目介绍我们的经验教训以及如何建立一个成功的手移植项目:上肢血管化复合体异体移植(VCA)二十年的全球经验表明,经过仔细筛选的患者的功能效果和生活质量都得到了改善。尽管最初人们对血管化复合肢体移植持保留态度,但美国已有30多名患者从手部移植中受益,其中约80%的患者获得了长期成功。我们有四位接受过双侧上肢同种异体移植手术的患者。这篇综述文章重点介绍了我们在上肢同种异体移植团队组建、后勤、患者选择、围手术期计划、手术过程和术后管理等方面的个人经验和教训。摘要:持续学习和严格评估对于保持上肢同种异体移植项目的成功至关重要。总结:持续学习和批判性评估对维持成功的上肢动静脉联合术至关重要,这将确保能从这一改善生命的手术中获益最多的患者被识别出来,并对其他患者进行优化,以获得尽可能好的治疗效果。
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Establishing an upper extremity transplantation program: lessons learnt over 12 years.

Purpose of review: As one of the early hand transplant programs in the world, we are often asked to educate other programs on the lessons we have learned and on how to set up a successful hand transplantation program.

Recent findings: Two decades of global experience with vascularized composite allotransplantation (VCA) of the upper limb have demonstrated improved functional outcomes and quality of life for carefully screened patients. Despite initial reticence about VCA, over 30 patients in the USA have benefited from hand transplantation, with around 80% long-term successes. We have experience with four bilateral upper extremity patients who have undergone bilateral upper extremity allotransplants. This review article highlights our personal experience and lessons with respect to VCA team assembly, logistics, patient selection, perioperative planning, the operative procedure, and postoperative management.

Summary: Continual learning and critical evaluation are crucial to maintaining a successful upper extremity VCA program. This will ensure that patients who stand to benefit most from this life-enhancing procedure are identified and are others optimized to achieve the best possible outcomes.

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来源期刊
CiteScore
4.10
自引率
4.50%
发文量
124
审稿时长
6-12 weeks
期刊介绍: ​​​​​​Current Opinion in Organ Transplantation is an indispensable resource featuring key, up-to-date and important advances in the field from around the world. Led by renowned guest editors for each section, every bimonthly issue of Current Opinion in Organ Transplantation delivers a fresh insight into topics such as stem cell transplantation, immunosuppression, tolerance induction and organ preservation and procurement. With 18 sections in total, the journal provides a convenient and thorough review of the field and will be of interest to researchers, surgeons and other healthcare professionals alike.
期刊最新文献
Ethical considerations in lung re-transplantation. Ethics of abortion in transplantation. Establishing an upper extremity transplantation program: lessons learnt over 12 years. The current state of tolerance induction in vascularized composite allotransplantation. Tracheal transplantation: lessons learned that may apply to lung transplantation.
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