Anna-Lisa V Nguyen, Mahmoud Moustafa, David-Dan Nguyen, David Bouhadana, Tuan Thanh Nguyen, Bilal Chughtai, Dean S Elterman, Christopher J D Wallis, Quoc-Dien Trinh, Naeem Bhojani
{"title":"在治疗良性前列腺增生症的真正微创手术疗法的临床试验中没有种族/族裔报告。","authors":"Anna-Lisa V Nguyen, Mahmoud Moustafa, David-Dan Nguyen, David Bouhadana, Tuan Thanh Nguyen, Bilal Chughtai, Dean S Elterman, Christopher J D Wallis, Quoc-Dien Trinh, Naeem Bhojani","doi":"10.1016/j.urology.2024.09.043","DOIUrl":null,"url":null,"abstract":"<p><strong>Objective: </strong>To assess the extent of racial reporting and enrolment in RCTs of minimally invasive surgical therapies (MIST) for the office-based treatment of benign prostatic hyperplasia (BPH).</p><p><strong>Methods: </strong>A systematic review was conducted for RCTs assessing six office-based MISTs: transurethral microwave thermotherapy, prostatic artery embolization, prostatic urethral lift, temporary implantable nitinol device, water vapor thermal therapy, and Optilume. MEDLINE, Embase, and the Cochrane CENTRAL databases were searched up to November 3rd, 2023. Publications were excluded if they 1) did not address one of the aforementioned office-based MISTs for the treatment of BPH; 2) were not RCTs; 3) were an abstract or conference proceeding; or 4) were not published in English. In addition to study characteristics, data about racial reporting was collected. Two independent reviewers completed screening at title, abstract, and full-text levels, with conflicts resolved by consensus with a third reviewer.</p><p><strong>Results: </strong>A total of 61 publications representing 37 unique RCTs (n=4027 unique patients) were reviewed, with publication years spanning from 1993 to 2023. TUMT was the most frequently studied MIST. Most publications (79%) were based solely in Europe or North America. Over 50% of the publications were multicenter trials. None of the included publications reported on race/ethnicity of study participants.</p><p><strong>Conclusion: </strong>None of the 61 included publications of RCTs of office-based MISTs provided information on racial/ethnic composition of study participants. There is a staggering gap in the standardization of race/ethnicity reporting and enrolment within RCTs of MISTs. More granular data on race/ethnicity allows for better generalizability and equity.</p>","PeriodicalId":23415,"journal":{"name":"Urology","volume":null,"pages":null},"PeriodicalIF":2.1000,"publicationDate":"2024-10-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Absence of race/ethnicity reporting in clinical trials of true minimally invasive surgical therapies for the treatment of benign prostatic hyperplasia.\",\"authors\":\"Anna-Lisa V Nguyen, Mahmoud Moustafa, David-Dan Nguyen, David Bouhadana, Tuan Thanh Nguyen, Bilal Chughtai, Dean S Elterman, Christopher J D Wallis, Quoc-Dien Trinh, Naeem Bhojani\",\"doi\":\"10.1016/j.urology.2024.09.043\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Objective: </strong>To assess the extent of racial reporting and enrolment in RCTs of minimally invasive surgical therapies (MIST) for the office-based treatment of benign prostatic hyperplasia (BPH).</p><p><strong>Methods: </strong>A systematic review was conducted for RCTs assessing six office-based MISTs: transurethral microwave thermotherapy, prostatic artery embolization, prostatic urethral lift, temporary implantable nitinol device, water vapor thermal therapy, and Optilume. MEDLINE, Embase, and the Cochrane CENTRAL databases were searched up to November 3rd, 2023. Publications were excluded if they 1) did not address one of the aforementioned office-based MISTs for the treatment of BPH; 2) were not RCTs; 3) were an abstract or conference proceeding; or 4) were not published in English. In addition to study characteristics, data about racial reporting was collected. Two independent reviewers completed screening at title, abstract, and full-text levels, with conflicts resolved by consensus with a third reviewer.</p><p><strong>Results: </strong>A total of 61 publications representing 37 unique RCTs (n=4027 unique patients) were reviewed, with publication years spanning from 1993 to 2023. TUMT was the most frequently studied MIST. Most publications (79%) were based solely in Europe or North America. Over 50% of the publications were multicenter trials. None of the included publications reported on race/ethnicity of study participants.</p><p><strong>Conclusion: </strong>None of the 61 included publications of RCTs of office-based MISTs provided information on racial/ethnic composition of study participants. There is a staggering gap in the standardization of race/ethnicity reporting and enrolment within RCTs of MISTs. More granular data on race/ethnicity allows for better generalizability and equity.</p>\",\"PeriodicalId\":23415,\"journal\":{\"name\":\"Urology\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":2.1000,\"publicationDate\":\"2024-10-04\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Urology\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1016/j.urology.2024.09.043\",\"RegionNum\":3,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"UROLOGY & NEPHROLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Urology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1016/j.urology.2024.09.043","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"UROLOGY & NEPHROLOGY","Score":null,"Total":0}
Absence of race/ethnicity reporting in clinical trials of true minimally invasive surgical therapies for the treatment of benign prostatic hyperplasia.
Objective: To assess the extent of racial reporting and enrolment in RCTs of minimally invasive surgical therapies (MIST) for the office-based treatment of benign prostatic hyperplasia (BPH).
Methods: A systematic review was conducted for RCTs assessing six office-based MISTs: transurethral microwave thermotherapy, prostatic artery embolization, prostatic urethral lift, temporary implantable nitinol device, water vapor thermal therapy, and Optilume. MEDLINE, Embase, and the Cochrane CENTRAL databases were searched up to November 3rd, 2023. Publications were excluded if they 1) did not address one of the aforementioned office-based MISTs for the treatment of BPH; 2) were not RCTs; 3) were an abstract or conference proceeding; or 4) were not published in English. In addition to study characteristics, data about racial reporting was collected. Two independent reviewers completed screening at title, abstract, and full-text levels, with conflicts resolved by consensus with a third reviewer.
Results: A total of 61 publications representing 37 unique RCTs (n=4027 unique patients) were reviewed, with publication years spanning from 1993 to 2023. TUMT was the most frequently studied MIST. Most publications (79%) were based solely in Europe or North America. Over 50% of the publications were multicenter trials. None of the included publications reported on race/ethnicity of study participants.
Conclusion: None of the 61 included publications of RCTs of office-based MISTs provided information on racial/ethnic composition of study participants. There is a staggering gap in the standardization of race/ethnicity reporting and enrolment within RCTs of MISTs. More granular data on race/ethnicity allows for better generalizability and equity.
期刊介绍:
Urology is a monthly, peer–reviewed journal primarily for urologists, residents, interns, nephrologists, and other specialists interested in urology
The mission of Urology®, the "Gold Journal," is to provide practical, timely, and relevant clinical and basic science information to physicians and researchers practicing the art of urology worldwide. Urology® publishes original articles relating to adult and pediatric clinical urology as well as to clinical and basic science research. Topics in Urology® include pediatrics, surgical oncology, radiology, pathology, erectile dysfunction, infertility, incontinence, transplantation, endourology, andrology, female urology, reconstructive surgery, and medical oncology, as well as relevant basic science issues. Special features include rapid communication of important timely issues, surgeon''s workshops, interesting case reports, surgical techniques, clinical and basic science review articles, guest editorials, letters to the editor, book reviews, and historical articles in urology.