早期吡非尼酮治疗可增强特发性肺纤维化患者的肺功能。

IF 1 4区 医学 Q3 MEDICINE, GENERAL & INTERNAL World Journal of Clinical Cases Pub Date : 2024-10-06 DOI:10.12998/wjcc.v12.i28.6247
Jin-Wei Zhang
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引用次数: 0

摘要

这篇社论对 Lei 等人发表的关于早期使用吡非尼酮治疗对特发性肺纤维化(IPF)患者肺功能疗效的研究发表了评论。该研究评估了吡非尼酮早期治疗对 IPF 患者肺功能的疗效。界定了 IPF 的早期和晚期阶段,强调了该药物的益处。虽然之前的研究表明吡非尼酮对晚期 IPF 有效,但本研究重点关注其在早期阶段的优势。研究强调了计算机断层扫描成像与生化数据和肺功能测试对于全面分析症状缓解情况的重要性。研究结果表明,使用吡非尼酮进行早期干预可明显减少疾病进展并保护肺功能,这突出了吡非尼酮作为早期 IPF 重要治疗策略的潜力。
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Early pirfenidone treatment enhances lung function in idiopathic pulmonary fibrosis patients.

This editorial comments on the study by Lei et al investigating the efficacy of early treatment with pirfenidone on the lung function of patients with idiopathic pulmonary fibrosis (IPF) published. This study evaluates the efficacy of early treatment with pirfenidone on lung function in patients with IPF. The early and advanced stages of IPF are defined, highlighting the drug's benefits. While prior research indicates pirfenidone's effectiveness in advanced IPF, this study focuses on its advantages in early stages. The study emphasizes the importance of computed tomography imaging alongside biochemical data and lung function tests for a comprehensive analysis of symptom relief. Results show that early intervention with pirfenidone significantly reduces disease progression and preserves lung function, underscoring its potential as a critical treatment strategy in early IPF.

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来源期刊
World Journal of Clinical Cases
World Journal of Clinical Cases Medicine-General Medicine
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期刊介绍: The World Journal of Clinical Cases (WJCC) is a high-quality, peer reviewed, open-access journal. The primary task of WJCC is to rapidly publish high-quality original articles, reviews, editorials, and case reports in the field of clinical cases. In order to promote productive academic communication, the peer review process for the WJCC is transparent; to this end, all published manuscripts are accompanied by the anonymized reviewers’ comments as well as the authors’ responses. The primary aims of the WJCC are to improve diagnostic, therapeutic and preventive modalities and the skills of clinicians and to guide clinical practice in clinical cases.
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