Ricardo Augusto Barbieri, Fabio Augusto Barbieri, Nicolle Zelada-Astudillo, Vinicius Christianini Moreno, Carlos Augusto Kalva-Filho, Antonio Roberto Zamunér
{"title":"有氧运动对帕金森病患者功能能力和最大摄氧量的影响:系统回顾和荟萃分析。","authors":"Ricardo Augusto Barbieri, Fabio Augusto Barbieri, Nicolle Zelada-Astudillo, Vinicius Christianini Moreno, Carlos Augusto Kalva-Filho, Antonio Roberto Zamunér","doi":"10.1016/j.apmr.2024.09.013","DOIUrl":null,"url":null,"abstract":"<p><strong>Objective: </strong>to determine the effects of aerobic training in randomized controlled clinical trials on functional capacity, motor symptoms, and oxygen consumption in individuals with PD through a systematic literature review and meta-analysis.</p><p><strong>Data sources: </strong>PUBMED, Web of Science, CINAHL, SciELO, and Medline databases were searched to identify published studies until September 2023.</p><p><strong>Study selection: </strong>Randomized controlled clinical trials that evaluated the long-term effect of aerobic exercise in individuals with PD were included.</p><p><strong>Data extraction: </strong>Two independent reviewers extracted the data, assessed the risk of bias and the Grading of Recommendation Assessment, Development, and Evaluation (GRADE). In case of disagreement, a third reviewer was consulted.</p><p><strong>Data synthesis: </strong>13 studies were included in the systematic review and the number of participants was 588 with an average age of 66.2 years (57 to 73 years). The study's exercise intervention lasted between 6 to 70 weeks, with most studies lasting 10-12 weeks, with three sessions/week and an average duration of 47 minutes/session. The meta-analysis revealed that aerobic exercise is effective in enhancing maximal oxygen uptake (SMD 0.42 [CI95% = 0.18, 0.66; p = 0.0007]) and functional capacity (SMD 0.48 [CI95% = 0.24-0.71; p < 0.0001]). In addition, aerobic exercise can reduce the UPDRS III (mean difference -2.48 [CI95% = -3.16, -1.81; p < 0.00001]) score in individuals with PD.</p><p><strong>Conclusion: </strong>Aerobic exercise training conducted 2 to 3 times a week, with different intensities (low to high) can be an effective intervention for enhancing functional capacity, maximizing oxygen uptake, and reducing the UPDRS scores in individuals with Parkinson's disease (PD).</p>","PeriodicalId":8313,"journal":{"name":"Archives of physical medicine and rehabilitation","volume":null,"pages":null},"PeriodicalIF":3.6000,"publicationDate":"2024-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Influence of aerobic exercise on functional capacity and maximal oxygen uptake in patients with Parkinson's disease: a systematic review and meta-analysis.\",\"authors\":\"Ricardo Augusto Barbieri, Fabio Augusto Barbieri, Nicolle Zelada-Astudillo, Vinicius Christianini Moreno, Carlos Augusto Kalva-Filho, Antonio Roberto Zamunér\",\"doi\":\"10.1016/j.apmr.2024.09.013\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Objective: </strong>to determine the effects of aerobic training in randomized controlled clinical trials on functional capacity, motor symptoms, and oxygen consumption in individuals with PD through a systematic literature review and meta-analysis.</p><p><strong>Data sources: </strong>PUBMED, Web of Science, CINAHL, SciELO, and Medline databases were searched to identify published studies until September 2023.</p><p><strong>Study selection: </strong>Randomized controlled clinical trials that evaluated the long-term effect of aerobic exercise in individuals with PD were included.</p><p><strong>Data extraction: </strong>Two independent reviewers extracted the data, assessed the risk of bias and the Grading of Recommendation Assessment, Development, and Evaluation (GRADE). In case of disagreement, a third reviewer was consulted.</p><p><strong>Data synthesis: </strong>13 studies were included in the systematic review and the number of participants was 588 with an average age of 66.2 years (57 to 73 years). The study's exercise intervention lasted between 6 to 70 weeks, with most studies lasting 10-12 weeks, with three sessions/week and an average duration of 47 minutes/session. The meta-analysis revealed that aerobic exercise is effective in enhancing maximal oxygen uptake (SMD 0.42 [CI95% = 0.18, 0.66; p = 0.0007]) and functional capacity (SMD 0.48 [CI95% = 0.24-0.71; p < 0.0001]). In addition, aerobic exercise can reduce the UPDRS III (mean difference -2.48 [CI95% = -3.16, -1.81; p < 0.00001]) score in individuals with PD.</p><p><strong>Conclusion: </strong>Aerobic exercise training conducted 2 to 3 times a week, with different intensities (low to high) can be an effective intervention for enhancing functional capacity, maximizing oxygen uptake, and reducing the UPDRS scores in individuals with Parkinson's disease (PD).</p>\",\"PeriodicalId\":8313,\"journal\":{\"name\":\"Archives of physical medicine and rehabilitation\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":3.6000,\"publicationDate\":\"2024-10-05\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Archives of physical medicine and rehabilitation\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1016/j.apmr.2024.09.013\",\"RegionNum\":2,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"REHABILITATION\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Archives of physical medicine and rehabilitation","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1016/j.apmr.2024.09.013","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"REHABILITATION","Score":null,"Total":0}
Influence of aerobic exercise on functional capacity and maximal oxygen uptake in patients with Parkinson's disease: a systematic review and meta-analysis.
Objective: to determine the effects of aerobic training in randomized controlled clinical trials on functional capacity, motor symptoms, and oxygen consumption in individuals with PD through a systematic literature review and meta-analysis.
Data sources: PUBMED, Web of Science, CINAHL, SciELO, and Medline databases were searched to identify published studies until September 2023.
Study selection: Randomized controlled clinical trials that evaluated the long-term effect of aerobic exercise in individuals with PD were included.
Data extraction: Two independent reviewers extracted the data, assessed the risk of bias and the Grading of Recommendation Assessment, Development, and Evaluation (GRADE). In case of disagreement, a third reviewer was consulted.
Data synthesis: 13 studies were included in the systematic review and the number of participants was 588 with an average age of 66.2 years (57 to 73 years). The study's exercise intervention lasted between 6 to 70 weeks, with most studies lasting 10-12 weeks, with three sessions/week and an average duration of 47 minutes/session. The meta-analysis revealed that aerobic exercise is effective in enhancing maximal oxygen uptake (SMD 0.42 [CI95% = 0.18, 0.66; p = 0.0007]) and functional capacity (SMD 0.48 [CI95% = 0.24-0.71; p < 0.0001]). In addition, aerobic exercise can reduce the UPDRS III (mean difference -2.48 [CI95% = -3.16, -1.81; p < 0.00001]) score in individuals with PD.
Conclusion: Aerobic exercise training conducted 2 to 3 times a week, with different intensities (low to high) can be an effective intervention for enhancing functional capacity, maximizing oxygen uptake, and reducing the UPDRS scores in individuals with Parkinson's disease (PD).
期刊介绍:
The Archives of Physical Medicine and Rehabilitation publishes original, peer-reviewed research and clinical reports on important trends and developments in physical medicine and rehabilitation and related fields. This international journal brings researchers and clinicians authoritative information on the therapeutic utilization of physical, behavioral and pharmaceutical agents in providing comprehensive care for individuals with chronic illness and disabilities.
Archives began publication in 1920, publishes monthly, and is the official journal of the American Congress of Rehabilitation Medicine. Its papers are cited more often than any other rehabilitation journal.