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引用次数: 0
摘要
随着硬件和软件的发展,单光子发射计算机断层扫描(SPECT)/X 射线计算机断层扫描(CT)技术飞速发展。临床应用的需求推动了这种增长,并为临床开发提供了灵感,特别是随着治疗学作用的不断扩大。全身定量重建、数字探测器和最新的多探头三维几何图形等技术的发展,使 SPECT 在许多方面都能与 PET 相媲美,尤其是在规划和评估放射性核素治疗的生物分布和剂量学研究中发挥了重要作用。尽管SPECT仍面临着空间分辨率和灵敏度有限等基本挑战,但由于它能对长寿命放射性同位素进行成像和同时进行多示踪剂研究,再加上设备易于获得,因此SPECT/CT是一项宝贵的临床资产。本综述将讨论 SPECT/CT 技术的发展及其临床影响。
Both hardware and software developments have seen single photon emission computed tomography (SPECT)/X-ray computed tomography (CT) technology grow at a rapid rate. Such growth has been fuelled by the need for clinical applications and has provided inspiration for clinical developments, particularly with the expanding role of theranostics. Developments such as whole-body quantitative reconstructions, digital detectors, and recent multidetector 3D geometry have allowed SPECT to become comparable to PET on a number of fronts, with a particularly powerful role in biodistribution and dosimetry studies for both planning and evaluating radionuclide therapy. Whilst there remain fundamental challenges for SPECT such the limited spatial resolution and sensitivity, the unique opportunity to image long-lived radioisotopes and simultaneous multi-tracer studies, together with easily accessible equipment, makes SPECT/CT a valuable clinical asset. This review discusses developments in SPECT/CT technology and their clinical impact.
期刊介绍:
BJR is the international research journal of the British Institute of Radiology and is the oldest scientific journal in the field of radiology and related sciences.
Dating back to 1896, BJR’s history is radiology’s history, and the journal has featured some landmark papers such as the first description of Computed Tomography "Computerized transverse axial tomography" by Godfrey Hounsfield in 1973. A valuable historical resource, the complete BJR archive has been digitized from 1896.
Quick Facts:
- 2015 Impact Factor – 1.840
- Receipt to first decision – average of 6 weeks
- Acceptance to online publication – average of 3 weeks
- ISSN: 0007-1285
- eISSN: 1748-880X
Open Access option