Yousra M Alturki, Hala T Jawa, Ghidaa A Alghamdi, Teyf M Althubiani, Mohammed T Bakhsh, Hassan M Alqurashi, Ahmed A Imam, Yaser M Elhams, Ahmed R Algethami, Omar M Babateen, Abdullah A Tawakul
{"title":"视神经炎的临床结果:沙特阿拉伯一家三级医疗中心的回顾性研究。","authors":"Yousra M Alturki, Hala T Jawa, Ghidaa A Alghamdi, Teyf M Althubiani, Mohammed T Bakhsh, Hassan M Alqurashi, Ahmed A Imam, Yaser M Elhams, Ahmed R Algethami, Omar M Babateen, Abdullah A Tawakul","doi":"10.17712/nsj.2024.4.20230119","DOIUrl":null,"url":null,"abstract":"<p><strong>Objectives: </strong>To investigate the clinical results of optic neuritis (ON) patients in a tertiary medical facility in Makkah, Kingdom of Saudi Arabia.</p><p><strong>Methods: </strong>The data of patients assessed for ON at Makkah, Saudi Arabia's King Abdullah Medical Center (KAMC), was examined retrospectively.</p><p><strong>Results: </strong>We identified 15 patients with ON. The ON was caused by multiple sclerosis (MS) in 73.3% of patients and neuromyelitis optica spectrum disorder (NMOSD) in 26.7% of patients. The disease was bilateral in 60% of patients and unilateral in 40% of patients. Additionally, 60% of patients had 2 or more episodes of ON, whereas 40% had a single episode. Patients with ON who presented with painful eye movements had a significantly longer disease duration (<i>p</i>=0.032). Moreover, patients whose disease duration was 11-15 days did not achieve a complete resolution of their symptoms and experienced some residual vision loss compared to 30.8% who had continued visual changes (<i>p</i>=0.049).</p><p><strong>Conclusion: </strong>In the studied population, multiple sclerosis was the most prevalent cause of ON. Women were more likely to have ON. The prognosis for eyesight was substantially connected with the length of ON.</p>","PeriodicalId":19284,"journal":{"name":"Neurosciences","volume":"29 4","pages":"224-230"},"PeriodicalIF":1.2000,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11460786/pdf/","citationCount":"0","resultStr":"{\"title\":\"Clinical outcomes of optic neuritis: A retrospective study at a tertiary medical center in Saudi Arabia.\",\"authors\":\"Yousra M Alturki, Hala T Jawa, Ghidaa A Alghamdi, Teyf M Althubiani, Mohammed T Bakhsh, Hassan M Alqurashi, Ahmed A Imam, Yaser M Elhams, Ahmed R Algethami, Omar M Babateen, Abdullah A Tawakul\",\"doi\":\"10.17712/nsj.2024.4.20230119\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Objectives: </strong>To investigate the clinical results of optic neuritis (ON) patients in a tertiary medical facility in Makkah, Kingdom of Saudi Arabia.</p><p><strong>Methods: </strong>The data of patients assessed for ON at Makkah, Saudi Arabia's King Abdullah Medical Center (KAMC), was examined retrospectively.</p><p><strong>Results: </strong>We identified 15 patients with ON. The ON was caused by multiple sclerosis (MS) in 73.3% of patients and neuromyelitis optica spectrum disorder (NMOSD) in 26.7% of patients. The disease was bilateral in 60% of patients and unilateral in 40% of patients. Additionally, 60% of patients had 2 or more episodes of ON, whereas 40% had a single episode. Patients with ON who presented with painful eye movements had a significantly longer disease duration (<i>p</i>=0.032). Moreover, patients whose disease duration was 11-15 days did not achieve a complete resolution of their symptoms and experienced some residual vision loss compared to 30.8% who had continued visual changes (<i>p</i>=0.049).</p><p><strong>Conclusion: </strong>In the studied population, multiple sclerosis was the most prevalent cause of ON. Women were more likely to have ON. The prognosis for eyesight was substantially connected with the length of ON.</p>\",\"PeriodicalId\":19284,\"journal\":{\"name\":\"Neurosciences\",\"volume\":\"29 4\",\"pages\":\"224-230\"},\"PeriodicalIF\":1.2000,\"publicationDate\":\"2024-10-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11460786/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Neurosciences\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.17712/nsj.2024.4.20230119\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"CLINICAL NEUROLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Neurosciences","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.17712/nsj.2024.4.20230119","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"CLINICAL NEUROLOGY","Score":null,"Total":0}
引用次数: 0
摘要
目的:调查沙特阿拉伯王国麦加市一家三级医疗机构的视神经炎(ON)患者的临床治疗效果:调查沙特阿拉伯王国麦加市一家三级医疗机构视神经炎(ON)患者的临床结果:方法:对沙特阿拉伯麦加阿卜杜拉国王医疗中心(KAMC)接受视神经炎评估的患者数据进行回顾性研究:结果:我们发现了 15 名 ON 患者。73.3%的患者是由多发性硬化症(MS)引起的,26.7%的患者是由神经脊髓炎视谱系障碍(NMOSD)引起的。60%的患者为双侧发病,40%的患者为单侧发病。此外,60%的患者出现过两次或两次以上的视神经亢进,而40%的患者只出现过一次视神经亢进。出现眼球运动疼痛的眼动亢进患者的病程明显较长(P=0.032)。此外,病程在11-15天的患者症状并未完全缓解,视力也有一定程度的下降,而30.8%的患者视力会持续变化(P=0.049):结论:在研究人群中,多发性硬化症是导致视网膜缺损的最常见原因。结论:在所研究的人群中,多发性硬化症是霰粒肿的最常见病因,女性更容易患霰粒肿。视力的预后与ON的时间长短有很大关系。
Clinical outcomes of optic neuritis: A retrospective study at a tertiary medical center in Saudi Arabia.
Objectives: To investigate the clinical results of optic neuritis (ON) patients in a tertiary medical facility in Makkah, Kingdom of Saudi Arabia.
Methods: The data of patients assessed for ON at Makkah, Saudi Arabia's King Abdullah Medical Center (KAMC), was examined retrospectively.
Results: We identified 15 patients with ON. The ON was caused by multiple sclerosis (MS) in 73.3% of patients and neuromyelitis optica spectrum disorder (NMOSD) in 26.7% of patients. The disease was bilateral in 60% of patients and unilateral in 40% of patients. Additionally, 60% of patients had 2 or more episodes of ON, whereas 40% had a single episode. Patients with ON who presented with painful eye movements had a significantly longer disease duration (p=0.032). Moreover, patients whose disease duration was 11-15 days did not achieve a complete resolution of their symptoms and experienced some residual vision loss compared to 30.8% who had continued visual changes (p=0.049).
Conclusion: In the studied population, multiple sclerosis was the most prevalent cause of ON. Women were more likely to have ON. The prognosis for eyesight was substantially connected with the length of ON.
期刊介绍:
Neurosciences is an open access, peer-reviewed, quarterly publication. Authors are invited to submit for publication articles reporting original work related to the nervous system, e.g., neurology, neurophysiology, neuroradiology, neurosurgery, neurorehabilitation, neurooncology, neuropsychiatry, and neurogenetics, etc. Basic research withclear clinical implications will also be considered. Review articles of current interest and high standard are welcomed for consideration. Prospective workshould not be backdated. There are also sections for Case Reports, Brief Communication, Correspondence, and medical news items. To promote continuous education, training, and learning, we include Clinical Images and MCQ’s. Highlights of international and regional meetings of interest, and specialized supplements will also be considered. All submissions must conform to the Uniform Requirements.