创伤性脾破裂:一份病例报告。

IF 0.7 Q3 MEDICINE, GENERAL & INTERNAL AME Case Reports Pub Date : 2024-08-17 eCollection Date: 2024-01-01 DOI:10.21037/acr-24-64
Jeremy Santarelli, Rami Alattar, Leslie R Elmore, Andrei I Gritsiuta, Jon R Henwood
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引用次数: 0

摘要

背景:与外伤相关的脾破裂在人群中很常见,但自发性脾破裂在临床实践中却很罕见。自发性脾破裂通常与血液病、肿瘤或感染性疾病有关,其中与 Epstein-Barr 病毒有关的传染性单核细胞增多症是全球最常见的病因。无潜在病因的自发性脾破裂被认为极为罕见。本文介绍了一例真正的自发性脾破裂病例:病例描述:本例患者为一名 73 岁女性,既往病史中曾患有甲状腺功能减退症、高血压、胸部鳞状细胞癌,并有吸烟史。腹部和盆腔无造影剂计算机断层扫描显示,急性脾脏损伤可能破裂,轮廓被血制品遮挡,伴有轻度至中度腹腔积血。医生决定对患者进行急诊剖腹探查术和脾脏切除术。患者接受了脾切除术后疫苗接种。复诊时,患者表现良好:本病例强调了早期诊断和治疗创伤性脾破裂的重要性,因为延误诊断和治疗会导致严重的发病率和死亡率。除了适当的抢救外,包括脾脏切除术在内的手术干预仍是治疗的主要手段。一些学者报道了血流动力学稳定的患者可以接受非手术治疗的病例,但其长期后果尚不清楚。由于罕见,创伤性自发性脾破裂在鉴别诊断中往往处于较低的位置。不幸的是,它具有很高的发病率和死亡率风险,因此及时诊断和干预势在必行。
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Atraumatic splenic rupture: a case report.

Background: Splenic rupture associated with trauma is common within the population, however, spontaneous splenic rupture is noted to be a rarity in clinical practice. Spontaneous splenic rupture is usually associated with hematologic, neoplastic, or infectious disorders, with infectious mononucleosis associated with Epstein-Barr virus being the most common cause worldwide. Spontaneous splenic rupture without underlying cause is thought to be exceedingly rare. In this article we present a case involving a true spontaneous splenic rupture.

Case description: We present the case of a 73-year-old female with past medical history significant for hypothyroidism, hypertension, squamous cell carcinoma of the chest, and history of tobacco use who presented to the emergency department with acute onset of left-sided flank pain radiating to her shoulder beginning three days prior. Computed tomography of the abdomen and pelvis without contrast revealed an acute splenic injury concerning for rupture with contour obscured by blood products with associated mild to moderate hemoperitoneum. The decision was made to proceed with emergent exploratory laparotomy and splenectomy. Patient received her post splenectomy vaccinations. On follow-up appointment, patient was noted to be doing well.

Conclusions: This case highlights the importance of early diagnosis and treatment of atraumatic splenic rupture, as delayed diagnosis and treatment is associated with significant morbidity and mortality. Operative intervention including splenectomy remains the mainstay of treatment, in addition to appropriate resuscitation. Some authors have reported cases in which hemodynamically stable patients are able to be treated non-operatively, however, the long-term consequences are unknown. Atraumatic spontaneous splenic rupture is often low on the differential diagnoses due to its rarity. Unfortunately, it carries a high risk of morbidity and mortality, and thus timely diagnosis and intervention is imperative.

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