提高效率和可持续性:在多组分反应中释放连续流的潜力。

IF 7.5 2区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY ChemSusChem Pub Date : 2024-10-11 DOI:10.1002/cssc.202401840
Marcelo H R Carvalho, Pedro P de Castro, Kleber T de Oliveira, Giovanni Wilson Amarante
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引用次数: 0

摘要

多组分反应 (MCR) 是合成复杂分子支架的一种快速高效的方法,将其与连续流动平台相结合是绿色合成领域日益公认的一种策略。这种结合可实现对反应参数的精确控制,包括改善动力学和选择性、缩短反应时间、提高产率和可扩展性,同时通过资源利用、废物最小化和减少对环境的影响,符合可持续发展和绿色化学的原则。本综述对 MCR-连续流联合反应的最新研究进行了批判性分析,重点关注实现更绿色、更可持续的合成实践。
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Enhancing Efficiency and Sustainability: Unleashing the Potential of Continuous Flow in Multicomponent Reactions.

The integration of multicomponent reactions (MCRs), which offer a rapid and efficient approach to synthesize complex molecular scaffolds, with continuous flow platforms is an increasingly recognized strategy in green synthesis. This association enables precise control over reaction parameters, including improved kinetics and selectivity, reduced reaction times, enhanced yields and scalabilities, while aligning with sustainable and green chemistry principles through resource utilization, minimized waste, and reduced environmental impact. This review presents a critical analysis of recent studies covering the MCR-continuous flow association, with a focus on achieving greener and more sustainable synthesis practices.

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来源期刊
ChemSusChem
ChemSusChem 化学-化学综合
CiteScore
15.80
自引率
4.80%
发文量
555
审稿时长
1.8 months
期刊介绍: ChemSusChem Impact Factor (2016): 7.226 Scope: Interdisciplinary journal Focuses on research at the interface of chemistry and sustainability Features the best research on sustainability and energy Areas Covered: Chemistry Materials Science Chemical Engineering Biotechnology
期刊最新文献
Aqueous-based assembly of plant-derived proteins yields a crosslinker-free biodegradable bioplastic consistent with green chemistry principles. Enhancing Efficiency and Sustainability: Unleashing the Potential of Continuous Flow in Multicomponent Reactions. Selective hydrogenation of furfural under mild conditions over single-atom Pd1/α-MoC catalyst. Catalytic Fe2+ Cation Pair Site for Base-free N-Alkylation of Aromatic Amines with Alcohols. Guidelines for Identifying the Structure of Heavy Phenolics in Lignin Depolymerization by Using High-Resolution Tandem Mass Spectrometry.
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