[利伯维尔大学医院艾滋病毒感染者视力受损的原因]。

Le Mali medical Pub Date : 2023-01-01
T Mba Aki, A D Mouinga Abayi, C Manomba Boulingui, P A Assoumou, E Anyunzoghe, M Vouma, I Mistoul, Mengome Mve
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引用次数: 0

摘要

导言:关于艾滋病病毒感染者(PLHIV)视力损伤(VI)问题的数据很少:目的:确定利伯维尔大学医院艾滋病病毒感染者(PLHIV)视力受损的原因:这是一项针对 737 名艾滋病病毒感染者(PLHIV)的观察性研究。研究参数包括年龄(岁)、性别、CD4计数、感染年龄、抗逆转录病毒疗法的使用情况以及远近视力(CMI-11)和VI病因:在 737 名艾滋病毒感染者中,有 75 人(101 只眼睛)患有视力障碍,医院患病率为 10.2%(n = 75/737)。其中34.7%(n = 26/75)的患者为双眼视力减退。主要病因是屈光障碍(47.5%)。16.8%的患者患有葡萄膜炎,其中12.9%是弓形虫引起的。其他病因包括白内障(11.9%)和巨细胞病毒视网膜炎(10.9%)。两名患者出现早期黄斑变性,另外两名患者出现黄斑缺血。此外,还观察到双侧黄斑出血和视网膜中央动脉闭塞:结论:每 10 名艾滋病毒感染者中就有一人视力受损。结论:每 10 名艾滋病毒感染者中就有一人视力受损,其中半数病例的病因是机会性疾病,主要是眼弓形虫病。常规筛查可改善视力预后。
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[Causes of visual impairment among people living with HIV at the University Hospital of Libreville].

Introduction: Few data exist on the issue of visual impairment (VI) in people living with HIV (PLHIV).

Objective: To identify the causes of visual impairment among people living with HIV (PLHIV) at the University Hospital of Libreville.

Population and methods: This was an observational study of 737 people living with HIV (PLHIV). The parameters studied were age (year), gender, CD4 count, age of infection, use of antiretroviral therapy as well as visual acuity from far and near (CMI-11) and cause of VI.

Results: Out of a population of 737 PLHIV, 75 (101 eyes) had VI, representing a hospital prevalence of 10.2% (n = 75/737). VI was bilateral for 34.7% (n = 26/75) of them. The main aetiology were refractive disorders (47.5%). Uveitis affected 16.8% of the number of eyes, of which 12.9% were of toxoplasmic origin. Other causes were cataracts (11.9%) and cytomegalovirus retinitis (10.9%). Two patients experienced early macular degeneration and two others with macular ischemia. Bilateral macular hemorrhage and occlusion of the central artery of the retina were also observed.

Conclusion: One in 10 PLHIV is visually impaired. In half of the cases, the pathologies that provide this handicap, are opportunistic disease with ocular toxoplasmosis in the foreground. Routine screening may improve visual prognosis.

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