揭示 1990-2021 年墨西哥妇女慢性肾病的负担。

IF 2.2 4区 医学 Q2 UROLOGY & NEPHROLOGY BMC Nephrology Pub Date : 2024-10-12 DOI:10.1186/s12882-024-03797-3
Claudio A Dávila-Cervantes, Marcela Agudelo-Botero
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引用次数: 0

摘要

背景:慢性肾脏病(CKD)已成为一个令人担忧的公共卫生问题,对人们的影响不分性别、年龄或社会经济地位。我们旨在分析 1990 年至 2021 年期间墨西哥女性慢性肾脏病的负担,具体表现为残疾生存年数(YLDs)、死亡率、生命损失年数(YLLs)和残疾调整生命年数(DALYs)。此外,我们还评估了残疾调整寿命年数与社会人口指数(SDI)和医疗质量指数(HAQI)之间的关系:方法:对 2021 年全球疾病负担、伤害和风险因素研究(GBD)的二手数据进行分析。我们使用死亡率、过早死亡导致的生命损失年数(YLLs)、残疾生存年数(YLDs)和残疾调整生命年数(DALYs)来分析 1990 年至 2021 年间女性的慢性肾脏病情况。我们使用对数线性分段回归模型来分析女性 CKD 残疾调整寿命年率随时间变化的趋势。这些信息按年龄组以及全国和 32 个州的子病因进行了分类。使用了年龄标准化比率(ASR):结果:1990 年至 2021 年间,在全国范围内,CKD 导致的 ASR 死亡率和 ASR-DALYs 显著增加。DALYs几乎完全由YLLs解释,这表明墨西哥很大一部分患有CKD的女性过早死亡。在国内不同州和不同年龄组中,这种疾病的负担存在差异。2021 年,ASR-DALY 率最高的是塔瓦斯科州(1,972.0),最低的是锡那罗亚州(865.1)。在大多数州,SDI 和 HAQI 与慢性肾脏病 DALYs 相关:结论:墨西哥妇女因慢性肾脏病而承受着巨大的负担,这反映在过早死亡和残疾年数上,而各州之间的差异需要加以解决,以减少不公平现象。在过去的 32 年中,社会经济指标以及医疗保健质量和可及性方面的改善无助于降低因慢性肾脏病导致的残疾调整寿命年数,这表明有必要调整政策方向,以对妇女的福祉和健康产生积极影响。
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Revealing the burden of chronic kidney disease in Mexican women, 1990-2021.

Background: Chronic kidney disease (CKD) has become a concerning public health issue, affecting people regardless of their sex, age, or socioeconomic status. We aimed to analyze the burden of female CKD in Mexico between 1990 and 2021, expressed in terms of years lived with disability (YLDs), mortality, years of life lost (YLLs), and disability-adjusted life-years (DALYs). Additionally, we evaluated the relationship between DALYs and the Socio-Demographic Index (SDI) and the Healthcare Access and Quality Index (HAQI).

Methods: Secondary data analysis from the Global Burden of Disease, Injuries, and Risk Factors Study (GBD) 2021. We used mortality, years of life lost due to premature mortality (YLLs), years lived with disability (YLDs), and disability-adjusted life years (DALYs to analyze CKD in women between 1990 and 2021. We used a log-linear segmented regression model to analyze trends in female CKD DALY rates over time. The information was disaggregated by age groups and sub-causes nationally and across the 32 states. Age-standardized rates (ASR) were used.

Results: Between 1990 and 2021, the ASR mortality and ASR-DALYs due to CKD increased significantly at the national level. The DALYs are almost entirely explained by YLLs, indicating that a large proportion of women with CKD in Mexico die prematurely. Disparities in the burden of this disease were observed across different states and age groups within the country. In 2021, the highest ASR-DALY rate was recorded in Tabasco (1,972.0), while the lowest was in Sinaloa (865.1). The SDI and HAQI were associated with the CKD DALYs in most states.

Conclusions: Mexican women experience a significant burden due to CKD, reflected in premature deaths and years lived with disability, while disparities between states need to be addressed to reduce inequities. Over the past 32 years, improvements in socioeconomic indicators and the quality and access to healthcare have not contributed to reducing the DALYs rate due to CKD, indicating a need to redirect policies to impact women's well-being and health positively.

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来源期刊
BMC Nephrology
BMC Nephrology UROLOGY & NEPHROLOGY-
CiteScore
4.30
自引率
0.00%
发文量
375
审稿时长
3-8 weeks
期刊介绍: BMC Nephrology is an open access journal publishing original peer-reviewed research articles in all aspects of the prevention, diagnosis and management of kidney and associated disorders, as well as related molecular genetics, pathophysiology, and epidemiology.
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