I. V. Fadeeva, Shachnoza Fuzailova, I. V. Dudenkov, P. V. Slukin, N. A. Andreeva, A. V. Knot’ko, D. V. Deyneko
{"title":"具有抗菌性能的刷石硼水泥","authors":"I. V. Fadeeva, Shachnoza Fuzailova, I. V. Dudenkov, P. V. Slukin, N. A. Andreeva, A. V. Knot’ko, D. V. Deyneko","doi":"10.1134/S2075113324700928","DOIUrl":null,"url":null,"abstract":"<p>Boron-containing brushite cements (B-BCs) for bone grafting based on boron-substituted β-tricalcium phosphate (B-TCP) are developed. The phase composition and microstructure of B-BCs are studied. It is shown that the crystalline phase of brushite is formed as a result of hardening of the cements. The behavior of B-BCs in a physiological saline containing a TRIS buffer is studied. The compression strength of B-BCs within 5 days after blending is 22.5 ± 1 MPa. Studies of antibacterial activity against the <i>E. coli</i> gram-negative strain ATCC25922 and <i>S. aureus</i> gram-positive strain ATCC25923 show that boron-containing brushite cement exhibits antibacterial activity against both strains, causing a decrease in the number of colony forming units (CFUs) already after 3 h of incubation. In vitro studies of the developed B-BCs are carried out, and it is shown that the developed cements based on TCP and B-TCP are biocompatible and promising for use in bone tissue surgery.</p>","PeriodicalId":586,"journal":{"name":"Inorganic Materials: Applied Research","volume":"15 5","pages":"1311 - 1316"},"PeriodicalIF":0.5000,"publicationDate":"2024-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Brushite Boron Cement with Antibacterial Properties\",\"authors\":\"I. V. Fadeeva, Shachnoza Fuzailova, I. V. Dudenkov, P. V. Slukin, N. A. Andreeva, A. V. Knot’ko, D. V. Deyneko\",\"doi\":\"10.1134/S2075113324700928\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p>Boron-containing brushite cements (B-BCs) for bone grafting based on boron-substituted β-tricalcium phosphate (B-TCP) are developed. The phase composition and microstructure of B-BCs are studied. It is shown that the crystalline phase of brushite is formed as a result of hardening of the cements. The behavior of B-BCs in a physiological saline containing a TRIS buffer is studied. The compression strength of B-BCs within 5 days after blending is 22.5 ± 1 MPa. Studies of antibacterial activity against the <i>E. coli</i> gram-negative strain ATCC25922 and <i>S. aureus</i> gram-positive strain ATCC25923 show that boron-containing brushite cement exhibits antibacterial activity against both strains, causing a decrease in the number of colony forming units (CFUs) already after 3 h of incubation. In vitro studies of the developed B-BCs are carried out, and it is shown that the developed cements based on TCP and B-TCP are biocompatible and promising for use in bone tissue surgery.</p>\",\"PeriodicalId\":586,\"journal\":{\"name\":\"Inorganic Materials: Applied Research\",\"volume\":\"15 5\",\"pages\":\"1311 - 1316\"},\"PeriodicalIF\":0.5000,\"publicationDate\":\"2024-10-09\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Inorganic Materials: Applied Research\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://link.springer.com/article/10.1134/S2075113324700928\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"MATERIALS SCIENCE, MULTIDISCIPLINARY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Inorganic Materials: Applied Research","FirstCategoryId":"1085","ListUrlMain":"https://link.springer.com/article/10.1134/S2075113324700928","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"MATERIALS SCIENCE, MULTIDISCIPLINARY","Score":null,"Total":0}
Brushite Boron Cement with Antibacterial Properties
Boron-containing brushite cements (B-BCs) for bone grafting based on boron-substituted β-tricalcium phosphate (B-TCP) are developed. The phase composition and microstructure of B-BCs are studied. It is shown that the crystalline phase of brushite is formed as a result of hardening of the cements. The behavior of B-BCs in a physiological saline containing a TRIS buffer is studied. The compression strength of B-BCs within 5 days after blending is 22.5 ± 1 MPa. Studies of antibacterial activity against the E. coli gram-negative strain ATCC25922 and S. aureus gram-positive strain ATCC25923 show that boron-containing brushite cement exhibits antibacterial activity against both strains, causing a decrease in the number of colony forming units (CFUs) already after 3 h of incubation. In vitro studies of the developed B-BCs are carried out, and it is shown that the developed cements based on TCP and B-TCP are biocompatible and promising for use in bone tissue surgery.
期刊介绍：
Inorganic Materials: Applied Research contains translations of research articles devoted to applied aspects of inorganic materials. Best articles are selected from four Russian periodicals: Materialovedenie, Perspektivnye Materialy, Fizika i Khimiya Obrabotki Materialov, and Voprosy Materialovedeniya and translated into English. The journal reports recent achievements in materials science: physical and chemical bases of materials science; effects of synergism in composite materials; computer simulations; creation of new materials (including carbon-based materials and ceramics, semiconductors, superconductors, composite materials, polymers, materials for nuclear engineering, materials for aircraft and space engineering, materials for quantum electronics, materials for electronics and optoelectronics, materials for nuclear and thermonuclear power engineering, radiation-hardened materials, materials for use in medicine, etc.); analytical techniques; structure–property relationships; nanostructures and nanotechnologies; advanced technologies; use of hydrogen in structural materials; and economic and environmental issues. The journal also considers engineering issues of materials processing with plasma, high-gradient crystallization, laser technology, and ultrasonic technology. Currently the journal does not accept direct submissions, but submissions to one of the source journals is possible.
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