从亚洲角度看慢性皮肤病的负担：新加坡队列中的健康状况效用和生活质量评估

JAAD International Pub Date : 2024-08-23 DOI:10.1016/j.jdin.2024.07.020

Yik Weng Yew MBBS, PhD , John Barbieri MD, MBA , Suephy C. Chen MD, MS

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引用次数: 0

摘要

背景在医疗成本不断上涨的时代，了解皮肤病的健康状态效用对于健康经济评估至关重要。目的建立亚洲人慢性皮肤病效用值目录。方法这是一项横断面研究，研究对象为 2019 年 2 月至 2023 年 3 月期间在皮肤科门诊就诊并患有以下皮肤病之一的成年人：(1) 湿疹、(2) 银屑病、(3) 寻常痤疮、(4) 慢性荨麻疹、(5) 色素性疾病、(6) 脱发、(7) 病毒性疣、(8) 真菌感染和 (9) 瘢痕疙瘩。收集了人口和社会经济信息。测量了健康状况和效用（皮肤病生活质量指数、Skindex-16、EuroQol-5 Dimension、视觉模拟量表、时间权衡和支付意愿）。大多数患者（76.9%）是华人，其次是马来人（11.5%）。在所有疾病严重程度和大多数皮肤病方面，时间-权衡效用均低于 EuroQol-5 Dimension 效用。患者愿意为治疗银屑病、痤疮、脱发和瘢痕疙瘩等疾病的假想药物支付 740 美元或更多。结论本研究提供了皮肤病效用的目录，并强调了不同测量方法的优势和挑战。

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Burden of chronic skin disease from an Asian perspective: Assessment of health state utilities and quality of life in a Singapore cohort

Background

Understanding health state utilities of skin diseases is essential for health economic evaluations in an era of rising health care costs.

Objective

To create a catalog of utility values of chronic skin diseases among Asians.

Methods

This is a cross-sectional study of adults attending a dermatology outpatient clinic from February 2019 to March 2023 with one of the following skin diseases: (1) eczema, (2) psoriasis, (3) acne vulgaris, (4) chronic urticaria, (5) pigmentary disorders, (6) hair loss, (7) viral warts, (8) fungal infections, and (9) keloids. Demographic and socioeconomic information was collected. Health status and utilities (Dermatology Life Quality Index, Skindex-16, EuroQol-5 Dimension, visual analog scale, time-trade-off, and willingness-to-pay) were measured.

Results

A total of 183 patients with a median age of 35.5 (21-77 years) years were included. Majority (76.9%) were Chinese, followed by Malays (11.5%). The time-trade-off utilities were lower than EuroQol-5 Dimension utilities across all disease severity and most skin diseases. Patients were willing to pay $740 USD or more for a hypothetical drug to cure conditions such as psoriasis, acne, hair loss, and keloids.