{"title":"用于检测病原体、疾病生物标记物和重金属离子的电化学生物传感器的最新进展","authors":"Manoj Kumar Goshisht , Goutam Kumar Patra , Aabroo Mahal , Ajaya Kumar Singh , Shobha , Mahavir Parshad","doi":"10.1016/j.ica.2024.122403","DOIUrl":null,"url":null,"abstract":"<div><div>The excessive usage of chemicals has resulted in environmental pollution worldwide leading to several health issues. The continuous rise in multidrug-resistance (MDR) pathogens is further challenging global health. The detection of these harmful chemicals, pathogens, and disease biomarkers is essential to combat these challenges. In this review, we describe different electrochemical biosensors to detect pathogens, disease biomarkers, and heavy metal ions (HMIs). The review has been devised in three parts. The first part involves discussion of different types of electrochemical biosensors for detecting MDR pathogens along with their mechanism of detection. The second part involves detection and monitoring of diabetes mellitus, cancer, and neurodegenerative diseases. The third part sheds light on the detection of heavy metal ions and monitoring of the environment. This review article has covered the literature based on different types of electrochemical biosensor, their working principles, mechanisms, and applications in detection of disease biomarkers, pathogens, and HMIs from 2017 to 2023.</div></div>","PeriodicalId":13599,"journal":{"name":"Inorganica Chimica Acta","volume":"574 ","pages":"Article 122403"},"PeriodicalIF":2.7000,"publicationDate":"2024-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Recent advances in electrochemical biosensors for the detection of pathogens, diseases biomarkers, and heavy metal ions\",\"authors\":\"Manoj Kumar Goshisht , Goutam Kumar Patra , Aabroo Mahal , Ajaya Kumar Singh , Shobha , Mahavir Parshad\",\"doi\":\"10.1016/j.ica.2024.122403\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><div>The excessive usage of chemicals has resulted in environmental pollution worldwide leading to several health issues. The continuous rise in multidrug-resistance (MDR) pathogens is further challenging global health. The detection of these harmful chemicals, pathogens, and disease biomarkers is essential to combat these challenges. In this review, we describe different electrochemical biosensors to detect pathogens, disease biomarkers, and heavy metal ions (HMIs). The review has been devised in three parts. The first part involves discussion of different types of electrochemical biosensors for detecting MDR pathogens along with their mechanism of detection. The second part involves detection and monitoring of diabetes mellitus, cancer, and neurodegenerative diseases. The third part sheds light on the detection of heavy metal ions and monitoring of the environment. This review article has covered the literature based on different types of electrochemical biosensor, their working principles, mechanisms, and applications in detection of disease biomarkers, pathogens, and HMIs from 2017 to 2023.</div></div>\",\"PeriodicalId\":13599,\"journal\":{\"name\":\"Inorganica Chimica Acta\",\"volume\":\"574 \",\"pages\":\"Article 122403\"},\"PeriodicalIF\":2.7000,\"publicationDate\":\"2024-10-09\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Inorganica Chimica Acta\",\"FirstCategoryId\":\"92\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0020169324004948\",\"RegionNum\":3,\"RegionCategory\":\"化学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"CHEMISTRY, INORGANIC & NUCLEAR\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Inorganica Chimica Acta","FirstCategoryId":"92","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0020169324004948","RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"CHEMISTRY, INORGANIC & NUCLEAR","Score":null,"Total":0}
Recent advances in electrochemical biosensors for the detection of pathogens, diseases biomarkers, and heavy metal ions
The excessive usage of chemicals has resulted in environmental pollution worldwide leading to several health issues. The continuous rise in multidrug-resistance (MDR) pathogens is further challenging global health. The detection of these harmful chemicals, pathogens, and disease biomarkers is essential to combat these challenges. In this review, we describe different electrochemical biosensors to detect pathogens, disease biomarkers, and heavy metal ions (HMIs). The review has been devised in three parts. The first part involves discussion of different types of electrochemical biosensors for detecting MDR pathogens along with their mechanism of detection. The second part involves detection and monitoring of diabetes mellitus, cancer, and neurodegenerative diseases. The third part sheds light on the detection of heavy metal ions and monitoring of the environment. This review article has covered the literature based on different types of electrochemical biosensor, their working principles, mechanisms, and applications in detection of disease biomarkers, pathogens, and HMIs from 2017 to 2023.
期刊介绍：
Inorganica Chimica Acta is an established international forum for all aspects of advanced Inorganic Chemistry. Original papers of high scientific level and interest are published in the form of Articles and Reviews.
Topics covered include:
• chemistry of the main group elements and the d- and f-block metals, including the synthesis, characterization and reactivity of coordination, organometallic, biomimetic, supramolecular coordination compounds, including associated computational studies;
• synthesis, physico-chemical properties, applications of molecule-based nano-scaled clusters and nanomaterials designed using the principles of coordination chemistry, as well as coordination polymers (CPs), metal-organic frameworks (MOFs), metal-organic polyhedra (MPOs);
• reaction mechanisms and physico-chemical investigations computational studies of metalloenzymes and their models;
• applications of inorganic compounds, metallodrugs and molecule-based materials.
Papers composed primarily of structural reports will typically not be considered for publication.
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