{"title":"多灶性结核并发抗合成酶综合征：发人深省的肿瘤鉴别诊断","authors":"Chang Dai, Yu Jiang, Weidong Lin, Yuhan Chen, Fangzhou Liu, Hai Deng, Yanlin Chen, Haowei Chen, Jieying Wang, Yunxia Lei, Shulin Wu, Yumei Xue","doi":"10.1002/med4.78","DOIUrl":null,"url":null,"abstract":"<p><i>Mycobacterium tuberculosis</i>, which mainly affects the lungs but can also invade other systems, presents a diagnostic challenge when co-existing with autoimmune disease. We report a case of 31-year-old Asian woman with anti-synthetase syndrome who developed abdominal and subcutaneous lumps during treatment, along with elevated tumor markers, raising suspicion of malignancy. Pathological examination revealed <i>M</i>. <i>tuberculosis</i> infection, changing the diagnosis to multifocal extrapulmonary tuberculosis. This case highlights the need for prompt and detailed evaluations, and the importance of broad differential diagnosis.</p>","PeriodicalId":100913,"journal":{"name":"Medicine Advances","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2024-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/med4.78","citationCount":"0","resultStr":"{\"title\":\"Anti-synthetase syndrome complicated by multifocal tuberculosis: A thought-provoking differential diagnosis with tumors\",\"authors\":\"Chang Dai, Yu Jiang, Weidong Lin, Yuhan Chen, Fangzhou Liu, Hai Deng, Yanlin Chen, Haowei Chen, Jieying Wang, Yunxia Lei, Shulin Wu, Yumei Xue\",\"doi\":\"10.1002/med4.78\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><i>Mycobacterium tuberculosis</i>, which mainly affects the lungs but can also invade other systems, presents a diagnostic challenge when co-existing with autoimmune disease. We report a case of 31-year-old Asian woman with anti-synthetase syndrome who developed abdominal and subcutaneous lumps during treatment, along with elevated tumor markers, raising suspicion of malignancy. Pathological examination revealed <i>M</i>. <i>tuberculosis</i> infection, changing the diagnosis to multifocal extrapulmonary tuberculosis. This case highlights the need for prompt and detailed evaluations, and the importance of broad differential diagnosis.</p>\",\"PeriodicalId\":100913,\"journal\":{\"name\":\"Medicine Advances\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2024-09-15\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://onlinelibrary.wiley.com/doi/epdf/10.1002/med4.78\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Medicine Advances\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://onlinelibrary.wiley.com/doi/10.1002/med4.78\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Medicine Advances","FirstCategoryId":"1085","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1002/med4.78","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Anti-synthetase syndrome complicated by multifocal tuberculosis: A thought-provoking differential diagnosis with tumors
Mycobacterium tuberculosis, which mainly affects the lungs but can also invade other systems, presents a diagnostic challenge when co-existing with autoimmune disease. We report a case of 31-year-old Asian woman with anti-synthetase syndrome who developed abdominal and subcutaneous lumps during treatment, along with elevated tumor markers, raising suspicion of malignancy. Pathological examination revealed M. tuberculosis infection, changing the diagnosis to multifocal extrapulmonary tuberculosis. This case highlights the need for prompt and detailed evaluations, and the importance of broad differential diagnosis.
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