A. Y. Ershov, I. V. Lagoda, A. A. Batyrenko, A. A. Martynenkov
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A Simple Method for the Synthesis of Pyrazolo[1,2-c]benzo-1,3,4-thiadiazepine Derivatives Based on Formaldehyde, Acrolein, and 2-Mercaptobenzoic Acid Hydrazide
The two-step method for the synthesis of previously unknown 1-hydroxy-2,3-dihydropyrazolo[1,2-c]benzo-1,3,4-thiadiazepin-11(5H)-one has been developed based on 2-mercaptobenzoic acid hydrazide and commercially available formaldehyde and acrolein. The synthesized compound, which has a targeted antitumor effect, is a promising bioactive co-ligand for obtaining gold glyco-nanoparticles for biomedical purposes.
期刊介绍：
Russian Journal of Organic Chemistry is an international peer reviewed journal that covers all aspects of modern organic chemistry including organic synthesis, theoretical organic chemistry, structure and mechanism, and the application of organometallic compounds in organic synthesis.
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