A. Y. Ershov, A. A. Martynenkov, I. V. Lagoda, A. A. Batyrenko
{"title":"应用 ANRORC 工艺定向合成 5-脲基-2-吡唑作为具有生物活性的金糖纳米粒子共配体","authors":"A. Y. Ershov, A. A. Martynenkov, I. V. Lagoda, A. A. Batyrenko","doi":"10.1134/S1070428024070194","DOIUrl":null,"url":null,"abstract":"<p>Interaction of 1-phenyl-4,6-dimethylpyrimidine-2(1<i>H</i>)-one with 4-mercaptobuturic acid hydrazide proceeds as ANRORC (Addition of the Nucleophile–Ring Opening–Ring Closure) process and results in the formation with 60% yield of 1-(4-mercaptobutanoyl)-3,5-dimethyl-5-(3-phenylcarbamoylamino)-2-pyrazoline as promising сo-ligand for the preparation of gold glyco-nanoparticles for biomedical purposes.</p>","PeriodicalId":766,"journal":{"name":"Russian Journal of Organic Chemistry","volume":null,"pages":null},"PeriodicalIF":0.8000,"publicationDate":"2024-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Application of the ANRORC Process for Directional Synthesis of 5-Ureido-2-pyrazolines as Biologically Active Co-Ligand of Gold Glyco-Nanoparticles\",\"authors\":\"A. Y. Ershov, A. A. Martynenkov, I. V. Lagoda, A. A. Batyrenko\",\"doi\":\"10.1134/S1070428024070194\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p>Interaction of 1-phenyl-4,6-dimethylpyrimidine-2(1<i>H</i>)-one with 4-mercaptobuturic acid hydrazide proceeds as ANRORC (Addition of the Nucleophile–Ring Opening–Ring Closure) process and results in the formation with 60% yield of 1-(4-mercaptobutanoyl)-3,5-dimethyl-5-(3-phenylcarbamoylamino)-2-pyrazoline as promising сo-ligand for the preparation of gold glyco-nanoparticles for biomedical purposes.</p>\",\"PeriodicalId\":766,\"journal\":{\"name\":\"Russian Journal of Organic Chemistry\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.8000,\"publicationDate\":\"2024-10-14\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Russian Journal of Organic Chemistry\",\"FirstCategoryId\":\"92\",\"ListUrlMain\":\"https://link.springer.com/article/10.1134/S1070428024070194\",\"RegionNum\":4,\"RegionCategory\":\"化学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"CHEMISTRY, ORGANIC\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Russian Journal of Organic Chemistry","FirstCategoryId":"92","ListUrlMain":"https://link.springer.com/article/10.1134/S1070428024070194","RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"CHEMISTRY, ORGANIC","Score":null,"Total":0}
Application of the ANRORC Process for Directional Synthesis of 5-Ureido-2-pyrazolines as Biologically Active Co-Ligand of Gold Glyco-Nanoparticles
Interaction of 1-phenyl-4,6-dimethylpyrimidine-2(1H)-one with 4-mercaptobuturic acid hydrazide proceeds as ANRORC (Addition of the Nucleophile–Ring Opening–Ring Closure) process and results in the formation with 60% yield of 1-(4-mercaptobutanoyl)-3,5-dimethyl-5-(3-phenylcarbamoylamino)-2-pyrazoline as promising сo-ligand for the preparation of gold glyco-nanoparticles for biomedical purposes.
期刊介绍：
Russian Journal of Organic Chemistry is an international peer reviewed journal that covers all aspects of modern organic chemistry including organic synthesis, theoretical organic chemistry, structure and mechanism, and the application of organometallic compounds in organic synthesis.
京公网安备 11010802042870号
京ICP备2023020795号-1
分享
求助内容：
应助结果提醒方式：
扫码关注我们
