{"title":"整合与征服：泛癌症蛋白质组学揭示癌症弱点和治疗机会","authors":"Debomita Chakraborty, Rossana Romero, Krishnaraj Rajalingam","doi":"10.1038/s41392-024-02009-6","DOIUrl":null,"url":null,"abstract":"<p>In a recent article published in <i>Cell</i> by Savage et al., the authors developed a computational workflow for integrating multi-omics data from readily available public online databases to provide novel insights into the proteogenomic landscape of several types of cancers and reveal new druggable targets for drug development or repurposing.<sup>1</sup></p>","PeriodicalId":40,"journal":{"name":"Inorganic Chemistry","volume":"229 1","pages":""},"PeriodicalIF":4.3000,"publicationDate":"2024-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Integrate and conquer: pan-cancer proteogenomics uncovers cancer vulnerabilities and therapeutic opportunities\",\"authors\":\"Debomita Chakraborty, Rossana Romero, Krishnaraj Rajalingam\",\"doi\":\"10.1038/s41392-024-02009-6\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p>In a recent article published in <i>Cell</i> by Savage et al., the authors developed a computational workflow for integrating multi-omics data from readily available public online databases to provide novel insights into the proteogenomic landscape of several types of cancers and reveal new druggable targets for drug development or repurposing.<sup>1</sup></p>\",\"PeriodicalId\":40,\"journal\":{\"name\":\"Inorganic Chemistry\",\"volume\":\"229 1\",\"pages\":\"\"},\"PeriodicalIF\":4.3000,\"publicationDate\":\"2024-10-15\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Inorganic Chemistry\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1038/s41392-024-02009-6\",\"RegionNum\":2,\"RegionCategory\":\"化学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"CHEMISTRY, INORGANIC & NUCLEAR\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Inorganic Chemistry","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1038/s41392-024-02009-6","RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CHEMISTRY, INORGANIC & NUCLEAR","Score":null,"Total":0}
Integrate and conquer: pan-cancer proteogenomics uncovers cancer vulnerabilities and therapeutic opportunities
In a recent article published in Cell by Savage et al., the authors developed a computational workflow for integrating multi-omics data from readily available public online databases to provide novel insights into the proteogenomic landscape of several types of cancers and reveal new druggable targets for drug development or repurposing.1
期刊介绍：
Inorganic Chemistry publishes fundamental studies in all phases of inorganic chemistry. Coverage includes experimental and theoretical reports on quantitative studies of structure and thermodynamics, kinetics, mechanisms of inorganic reactions, bioinorganic chemistry, and relevant aspects of organometallic chemistry, solid-state phenomena, and chemical bonding theory. Emphasis is placed on the synthesis, structure, thermodynamics, reactivity, spectroscopy, and bonding properties of significant new and known compounds.
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