{"title":"广泛的反CRISPR战略","authors":"Yi Zhang, Yue Feng","doi":"10.1038/s41589-024-01743-w","DOIUrl":null,"url":null,"abstract":"Prokaryotic CRISPR–Cas systems are counteracted by phage-encoded anti-CRISPR elements, and how they protect themselves remains enigmatic. A study shows that CRISPR-repressed toxins defend CRISPR–Cas against anti-CRISPR proteins or RNAs by inducing abortive infection.","PeriodicalId":18832,"journal":{"name":"Nature chemical biology","volume":"10 1","pages":""},"PeriodicalIF":12.9000,"publicationDate":"2024-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"A broad anti-anti-CRISPR strategy\",\"authors\":\"Yi Zhang, Yue Feng\",\"doi\":\"10.1038/s41589-024-01743-w\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Prokaryotic CRISPR–Cas systems are counteracted by phage-encoded anti-CRISPR elements, and how they protect themselves remains enigmatic. A study shows that CRISPR-repressed toxins defend CRISPR–Cas against anti-CRISPR proteins or RNAs by inducing abortive infection.\",\"PeriodicalId\":18832,\"journal\":{\"name\":\"Nature chemical biology\",\"volume\":\"10 1\",\"pages\":\"\"},\"PeriodicalIF\":12.9000,\"publicationDate\":\"2024-10-15\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Nature chemical biology\",\"FirstCategoryId\":\"99\",\"ListUrlMain\":\"https://doi.org/10.1038/s41589-024-01743-w\",\"RegionNum\":1,\"RegionCategory\":\"生物学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"BIOCHEMISTRY & MOLECULAR BIOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Nature chemical biology","FirstCategoryId":"99","ListUrlMain":"https://doi.org/10.1038/s41589-024-01743-w","RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"BIOCHEMISTRY & MOLECULAR BIOLOGY","Score":null,"Total":0}
Prokaryotic CRISPR–Cas systems are counteracted by phage-encoded anti-CRISPR elements, and how they protect themselves remains enigmatic. A study shows that CRISPR-repressed toxins defend CRISPR–Cas against anti-CRISPR proteins or RNAs by inducing abortive infection.
期刊介绍：
Nature Chemical Biology stands as an esteemed international monthly journal, offering a prominent platform for the chemical biology community to showcase top-tier original research and commentary. Operating at the crossroads of chemistry, biology, and related disciplines, chemical biology utilizes scientific ideas and approaches to comprehend and manipulate biological systems with molecular precision.
The journal embraces contributions from the growing community of chemical biologists, encompassing insights from chemists applying principles and tools to biological inquiries and biologists striving to comprehend and control molecular-level biological processes. We prioritize studies unveiling significant conceptual or practical advancements in areas where chemistry and biology intersect, emphasizing basic research, especially those reporting novel chemical or biological tools and offering profound molecular-level insights into underlying biological mechanisms.
Nature Chemical Biology also welcomes manuscripts describing applied molecular studies at the chemistry-biology interface due to the broad utility of chemical biology approaches in manipulating or engineering biological systems. Irrespective of scientific focus, we actively seek submissions that creatively blend chemistry and biology, particularly those providing substantial conceptual or methodological breakthroughs with the potential to open innovative research avenues. The journal maintains a robust and impartial review process, emphasizing thorough chemical and biological characterization.
京公网安备 11010802042870号
京ICP备2023020795号-1
分享
求助内容：
应助结果提醒方式：
扫码关注我们
