2000-2020 年美国年龄≥50 岁的成年人中慢性阻塞性肺病的流行率和发病率趋势

Yaxian Meng, Qianqian Ji, Aijie Zhang, Yiqiang Zhan
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引用次数: 0

摘要

背景 了解慢性阻塞性肺病(COPD)的患病率和发病率趋势对于改善慢性阻塞性肺病的控制和预防至关重要。我们旨在研究 2000-2020 年间美国 50 岁及以上成年人慢性阻塞性肺病患病率和发病率的变化趋势。 方法 利用健康与退休研究(Health and Retirement Study)的数据,我们分析了不同调查波次之间的慢性阻塞性肺病患病率,并计算了连续访谈波次之间的慢性阻塞性肺病发病率,按性别和种族进行了分层。我们采用连接点回归模型来研究慢性阻塞性肺病患病率和发病率的趋势。 结果 报告慢性阻塞性肺病的人群中,女性和白种人的比例较高。在整个研究期间,50 岁及以上成年人中经年龄调整后的慢性阻塞性肺病患病率呈上升趋势,从 2000 年的 9.02% 上升至 2020 年的 9.88%(平均两年百分比变化 [ABPC] = 0.41,95% 置信区间 [CI]:0.10, 0.71; p = 0.01).在整个研究期间,50 岁及以上成人慢性阻塞性肺病的年龄调整后发病率呈下降趋势,从 2000 年的每 10 万人年 1031.1 例降至 2020 年的每 10 万人年 700.5 例(ABPC = -1.63, 95% CI: -2.88, -0.36; p = 0.02)。 结论 我们的研究结果表明,自 2000 年以来,美国老年人的慢性阻塞性肺病患病率不断上升,而慢性阻塞性肺病的发病率却呈下降趋势。
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Trends in the prevalence and incidence of chronic obstructive pulmonary disease among adults aged ≥50 years in the United States, 2000–2020

Background

Understanding the trends of the prevalence and incidence rate of chronic obstructive pulmonary disease (COPD) is vital for improving the control and prevention of COPD. We aimed to examine the trends in the prevalence and incidence rate of COPD among adults aged 50 years or older in the United States during 2000–2020.

Methods

Utilizing data from the Health and Retirement Study, we analyzed COPD prevalence across survey waves and calculated COPD incidence rates between consecutive interview waves, stratified by gender and race. We employed joinpoint regression models to investigate trends in COPD prevalence and incidence.

Results

The individuals reporting COPD are more likely to be women and Caucasians. The age-adjusted prevalence of COPD among adults aged 50 years and over showed an increasing trend throughout the study period, spanning from 9.02% in 2000 to 9.88% in 2020 (average biennial percent change [ABPC] = 0.41, 95% confidence interval [CI]: 0.10, 0.71; p = 0.01). The age-adjusted incidence rate of COPD among adults aged 50 and over showed a decreasing trend throughout the study period 1031.1 per 100,000 person-years in 2000 to 700.5 per 100,000 person-years in 2020 (ABPC = −1.63, 95% CI: −2.88, −0.36; p = 0.02).

Conclusion

Our findings indicate a rising prevalence of COPD among older adults in the United States since 2000, while the incidence rate of COPD has shown a declining trend.

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来源期刊
CiteScore
6.70
自引率
0.00%
发文量
195
审稿时长
35 weeks
期刊介绍: This journal aims to promote progress from basic research to clinical practice and to provide a forum for communication among basic, translational, and clinical research practitioners and physicians from all relevant disciplines. Chronic diseases such as cardiovascular diseases, cancer, diabetes, stroke, chronic respiratory diseases (such as asthma and COPD), chronic kidney diseases, and related translational research. Topics of interest for Chronic Diseases and Translational Medicine include Research and commentary on models of chronic diseases with significant implications for disease diagnosis and treatment Investigative studies of human biology with an emphasis on disease Perspectives and reviews on research topics that discuss the implications of findings from the viewpoints of basic science and clinical practic.
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