脑脊液α-突触核蛋白种子扩增检测阳性与疾病进展和认知能力下降的关系:阿尔茨海默病神经影像学纵向研究

IF 13 1区 医学 Q1 CLINICAL NEUROLOGY Alzheimer's & Dementia Pub Date : 2024-10-20 DOI:10.1002/alz.14276
Duygu Tosun, Zachary Hausle, Pamela Thropp, Luis Concha-Marambio, Jennifer Lamoureux, Russ Lebovitz, Leslie M. Shaw, Andrew B. Singleton, Michael W. Weiner, , Cornelis Blauwendraat
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引用次数: 0

摘要

脑脊液(CSF)α-突触核蛋白(α-syn)种子扩增试验(SAA)是检测阿尔茨海默病路易体合并病理学的一种灵敏而特异的工具。
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Association of CSF α-synuclein seed amplification assay positivity with disease progression and cognitive decline: A longitudinal Alzheimer's Disease Neuroimaging Initiative study
Cerebrospinal fluid (CSF) α-synuclein (α-syn) seed amplification assay (SAA) is a sensitive and specific tool for detecting Lewy body co-pathology in Alzheimer's disease.
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来源期刊
Alzheimer's & Dementia
Alzheimer's & Dementia 医学-临床神经学
CiteScore
14.50
自引率
5.00%
发文量
299
审稿时长
3 months
期刊介绍: Alzheimer's & Dementia is a peer-reviewed journal that aims to bridge knowledge gaps in dementia research by covering the entire spectrum, from basic science to clinical trials to social and behavioral investigations. It provides a platform for rapid communication of new findings and ideas, optimal translation of research into practical applications, increasing knowledge across diverse disciplines for early detection, diagnosis, and intervention, and identifying promising new research directions. In July 2008, Alzheimer's & Dementia was accepted for indexing by MEDLINE, recognizing its scientific merit and contribution to Alzheimer's research.
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