电分析概述:霉酚酸盐和霉酚酸的传感。

IF 4.6 Q2 MATERIALS SCIENCE, BIOMATERIALS ACS Applied Bio Materials Pub Date : 2024-10-17 DOI:10.1039/D4AY01379D
Robert D. Crapnell and Craig E. Banks
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引用次数: 0

摘要

在本综述中,我们将探讨霉酚酸酯和霉酚酸的电分析测定方法。霉酚酸酯是霉酚酸的一种原药,是一种免疫抑制剂,用于降低接受器官移植的患者体内的天然免疫能力,也可用于治疗自身免疫性疾病。基于实验室的分析仪器提供了测量霉酚酸及其代谢物的常规方法,但仍有余地开发可与实验室设备相媲美的现场分析测量方法。电分析为提供高选择性和高灵敏度的结果提供了机会,而且成本效益高,可支持现场分析。在本综述中,我们概述了目前针对霉酚酸酯和霉酚酸测量的电分析研究,并对未来的研究提出了见解。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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Electroanalytical overview: the sensing of the mycophenolate mofetil and mycophenolic acid

In this review, we explore the electroanalytical determination of mycophenolate mofetil and mycophenolic acid. Mycophenolate mofetil is a prodrug of mycophenolic acid, which is an immunosuppressive agent used to lower the body's natural immunity in patients who receive organ transplants as well as to treat autoimmune conditions. Laboratory based analytical instrumentation provide a routine methodology to measure mycophenolate mofetil and its metabolites, but there is scope to develop in-the-field analytical measurements that are comparable to those from laboratory equipment. Electroanalysis provides an opportunity to provide highly selective and sensitive outputs but are cost-efficient and can support on-site analysis. In this review, we provide an electroanalytical overview of the current research directed toward the measurement of mycophenolate mofetil and mycophenolic acid, offering insights to future research.

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来源期刊
ACS Applied Bio Materials
ACS Applied Bio Materials Chemistry-Chemistry (all)
CiteScore
9.40
自引率
2.10%
发文量
464
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