一例 20 岁菲律宾女性系统性表皮痣(Nevus Unius Lateris)病例,采用二氧化碳烧蚀激光和外用曲安奈德治疗。

Q4 Medicine Acta Medica Philippina Pub Date : 2024-09-30 eCollection Date: 2024-01-01 DOI:10.47895/amp.v58i17.9232
Maria Emilia Ruth V Eusebio, Doha Mae Laurisse M Manalo-Legas, Emy Christine Onishi-Limchoa
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引用次数: 0

摘要

这是一例 20 岁女性的病例,她没有任何已知的合并症,出生时即出现疣状斑块,呈单侧白斑状分布。活组织检查结果与表皮痣一致,因此患者被诊断为系统性表皮痣,单侧晚期痣(Nevus Unius Lateris)型。金标准治疗方法是全层手术切除,但由于累及范围广,治疗这种疾病仍是一项挑战。因此,我们采用了二氧化碳激光消融术和 0.1% 曲安奈德外用药相结合的非手术疗法。较薄的病灶(1-3 毫米)复发率较低(50%),而较厚的病灶(大于 3 毫米)在 6 个月后复发率为 100%。因此,需要再次进行二氧化碳激光治疗。使用皮肤病生活质量指数(DLQI)测量了患者的生活质量,结果显示治疗后患者的生活质量提高了35%。
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A Case of Systematized Epidermal Nevus (Nevus Unius Lateris) in a 20-year-old Filipino Female Treated with Ablative CO2 Laser and Topical Tretinoin.

This is a case of a 20-year-old female with no known comorbidities presenting with verrucous plaques arranged in a unilateral blaschkoid distribution at birth. Biopsy was consistent with epidermal nevus hence patient was diagnosed as systematized epidermal nevus, Nevus Unius Lateris type. Gold standard treatment is full thickness surgical excision however, due to the extensive involvement, treatment of this condition remains a challenge. Hence, non-surgical combination of ablative CO2 laser and topical tretinoin 0.1% were done. Thinner lesions (1-3 mm) showed lower recurrence (50%) as compared to thicker lesions (>3 mm) showing 100% recurrence after six months. Hence, another CO2 laser session is needed. Quality of life was measured using the Dermatologic Life Quality Index (DLQI) with noted 35% improvement post-treatment.

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来源期刊
Acta Medica Philippina
Acta Medica Philippina Medicine-Medicine (all)
CiteScore
0.40
自引率
0.00%
发文量
199
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